Prevention of atherosclerosis is important because it is a risk factor for cardiovascular
diseases globally. One of the causes of atherosclerosis is accumulation of cholesterol and …

The prompt removal of apoptotic cells by phagocytes is important for maintaining tissue
homeostasis. The molecular and cellular events that underpin apoptotic cell recognition and …

ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of
phospholipids and cholesterol to the extracellular acceptor apolipoprotein AI (apoA-I) for …

Pharmacologic inhibition of acetyl‐CoA carboxylase (ACC) enzymes, ACC1 and ACC2,
offers an attractive therapeutic strategy for nonalcoholic fatty liver disease (NAFLD) through …

Cholesterol is essential for neuronal physiology, both during development and in the adult
life: as a major component of cell membranes and precursor of steroid hormones, it …

The metabolism of high-density lipoproteins (HDL), which are inversely related to risk of
atherosclerotic cardiovascular disease, involves a complex interplay of factors regulating …

Apolipoprotein E is associated with age-related risk for Alzheimer's disease and plays
critical roles in Aβ homeostasis. We report that ApoE plays a role in facilitating the proteolytic …

Objectives: This study was designed to assess the relationship of high-density-lipoprotein
cholesterol (HDL-C), HDL particle size, and apolipoprotein AI (apoA-I) with the occurrence of …

High-density lipoprotein heterogeneity and function in rever... : Current Opinion in Lipidology
High-density lipoprotein heterogeneity and function in reverse cholesterol transport : Current …

Blood high-density lipoprotein (HDL) levels are inversely related to risk for cardiovascular
disease, implying that factors associated with HDL metabolism are atheroprotective. One of …