Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids

AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

Stimuli responsive synthetic polypeptides derived from N-carboxyanhydride (NCA) polymerisation

J Huang, A Heise - Chemical Society Reviews, 2013 - pubs.rsc.org
The progress in NCA polymerisation combined with advanced orthogonal functionalization
techniques as well as the integration with other controlled polymerisation techniques …

Synthetic polymers

MC Hacker, J Krieghoff, AG Mikos - Principles of regenerative medicine, 2019 - Elsevier
Synthetic polymers are an important component of biomaterials used as implant materials,
drug delivery devices, and tissue engineering scaffolds or hydrogels. This chapter attempts …

Photoresponsive Poly(S-(o-nitrobenzyl)-l-cysteine)-b-PEO from a l-Cysteine N-Carboxyanhydride Monomer: Synthesis, Self-Assembly, and Phototriggered Drug …

G Liu, CM Dong - Biomacromolecules, 2012 - ACS Publications
A photoresponsive S-(o-nitrobenzyl)-l-cysteine N-carboxyanhydride (NBC-NCA) monomer
was for the first time designed, and the related poly (S-(o-nitrobenzyl)-l-cysteine)-b-poly …

A Facile Glovebox-Free Strategy To Significantly Accelerate the Syntheses of Well-Defined Polypeptides by N-Carboxyanhydride (NCA) Ring-Opening …

J Zou, J Fan, X He, S Zhang, H Wang… - Macromolecules, 2013 - ACS Publications
Synthetic polypeptides consisting of α-amino acids linked covalently have significant
similarities to natural materials, which have facilitated their utilization extensively in …

Supramolecular hydrogels with reverse thermal gelation properties from (oligo) tyrosine containing block copolymers

J Huang, CL Hastings, GP Duffy, HM Kelly… - …, 2013 - ACS Publications
Novel block copolymers comprising poly (ethylene glycol)(PEG) and an oligo (tyrosine)
block were synthesized in different compositions by N-carboxyanhydride (NCA) …

Molecular weight and architectural dependence of well-defined star-shaped poly (lysine) as a gene delivery vector

M Byrne, D Victory, A Hibbitts, M Lanigan… - Biomaterials …, 2013 - pubs.rsc.org
A series of well-defined star-shaped polypeptides were successfully synthesised by the ring
opening polymerisation (ROP) of the N-carboxyanhydride (NCA) of ε-carbobenzyloxy-L …

Ugi reaction of natural amino acids: a general route toward facile synthesis of polypeptoids for bioapplications

X Zhang, S Wang, J Liu, Z **e, S Luan, C **ao… - ACS Macro …, 2016 - ACS Publications
Polypeptoids represent a significant class of synthetic analogues of natural polypeptides
with potential biomimetic applications in materials, catalysis, and pharmaceuticals, but their …

Fe3+@polyDOPA-b-polysarcosine, a T1-Weighted MRI Contrast Agent via Controlled NTA Polymerization

Y Miao, F **e, J Cen, F Zhou, X Tao, J Luo… - ACS Macro …, 2018 - ACS Publications
α-Amino acid N-thiocarboxyanhydrides (NTAs) are promising cyclic monomers to synthesize
polypeptides and polypeptoids via controlled ring-opening polymerizations. Superior to N …

Chemoenzymatic synthesis of polypeptides for use as functional and structural materials

K Tsuchiya, K Numata - Macromolecular Bioscience, 2017 - Wiley Online Library
Polypeptides inspired by the natural functional and structural proteins present in living
systems are promising materials for various fields in terms of their versatile functionality and …