Facing the global “superbug” crisis due to the emergence and selection for antibiotic
resistance, phages are among the most promising solutions. Fighting multidrug-resistant …

The concept of genetic code expansion (GCE) has revolutionized the field of chemical and
synthetic biology, enabling the site-specific incorporation of noncanonical amino acids …

Engineered probiotics are an emerging platform for in situ delivery of therapeutics to the gut.
Herein, we developed an orally administered, yeast-based therapeutic delivery system to …

Noncanonical amino acids (ncAAs) are synthetic building blocks that, when incorporated
into proteins, confer novel functions and enable precise control over biological processes …

Exploiting electrogenic microorganisms as unconventional chassis hosts offers potential
solutions to global energy and environmental challenges. However, their limited …

Since the development of recombinant DNA technologies, the need to establish biosafety
and biosecurity measures to control genetically modified organisms has been clear …

Synthetic biology holds immense promise to tackle key problems in resource use,
environmental remediation, and human health care. However, comprehensive safety …

Non-canonical amino acids (ncAAs), as derivatives of canonical amino acids (cAAs), when
specifically incorporated into proteins, could enrich protein functions. Currently, ncAAs …

Background During the last decades, the advancements in synthetic biology opened the
doors for a profusion of cost-effective, fast, and ecologically friendly medical applications …

Substantial improvements in DNA sequencing and synthesis technologies and increased
understanding of genome biology have empowered the development of synthetic genomics …