Contribution of infrapatellar fat pad and synovial membrane to knee osteoarthritis pain

E Belluzzi, E Stocco, A Pozzuoli… - BioMed research …, 2019 - Wiley Online Library
Osteoarthritis (OA) is the most common form of joint disease and a major cause of pain and
disability in the adult population. Interestingly, there are patients with symptomatic OA …

The role of fibrosis in osteoarthritis progression

YA Rim, JH Ju - Life, 2020 - mdpi.com
Osteoarthritis (OA) is a chronic degenerative joint disease where the main characteristics
include cartilage degeneration and synovial membrane inflammation. These changes in the …

Infrapatellar fat pad gene expression and protein production in patients with and without osteoarthritis

E Belluzzi, V Macchi, CG Fontanella… - International journal of …, 2020 - mdpi.com
Osteoarthritis (OA) is one of the most common joint disorders. Evidence suggests that the
infrapatellar fat pad (IFP) is directly involved in OA pathology. However, a comparison …

Infrapatellar fat pad/synovium complex in early-stage knee osteoarthritis: potential new target and source of therapeutic mesenchymal stem/stromal cells

DN Greif, D Kouroupis, CJ Murdock… - … in bioengineering and …, 2020 - frontiersin.org
The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …

[HTML][HTML] The biphasic role of the infrapatellar fat pad in osteoarthritis

S Yue, G Zhai, S Zhao, X Liang, Y Liu, X Chen… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration. It is
a whole organ disease characterized by cartilage degeneration and varying degrees of …

Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis

J Li, T Gui, L Yao, H Guo, YL Lin, J Lu… - Journal of Bone and …, 2024 - academic.oup.com
Osteoarthritis (OA) affects multiple tissues in the knee joint, including the synovium and intra-
articular adipose tissue (IAAT) that are attached to each other. However, whether these two …

Association between infrapatellar fat pad ultrasound elasticity and anterior knee pain in patients with knee osteoarthritis

Y Satake, M Izumi, K Aso, M Ikeuchi - Scientific Reports, 2023 - nature.com
This study investigates whether infrapatellar fat pad (IPFP) elasticity is associated with
anterior knee pain in patients with knee osteoarthritis (KOA). The IPFP elasticity of 97 …

Mechanical behavior of infrapatellar fat pad of patients affected by osteoarthritis

CG Fontanella, E Belluzzi, A Pozzuoli, M Favero… - Journal of …, 2022 - Elsevier
The infrapatellar fat pad (IFP) is an adipose tissue present in the knee that lies between the
patella, femur, meniscus and tibia, filling the space between these structures. IFP facilitates …

The Corpus Adiposum Infrapatellare (Hoffa's Fat Pad)—the role of the infrapatellar fat pad in osteoarthritis pathogenesis

S Braun, F Zaucke, M Brenneis, AE Rapp, P Pollinger… - Biomedicines, 2022 - mdpi.com
In recent years, the infrapatellar fat pad (IFP) has gained increasing research interest. The
contribution of the IFP to the development and progression of knee osteoarthritis (OA) …

Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury

RF Bergman, L Lammlin, L Junginger, E Farrell… - Osteoarthritis and …, 2024 - Elsevier
Objective Osteoarthritis (OA) is a disease with sex-dependent prevalence and severity in
both human and animal models. We sought to elucidate sex differences in synovitis …