Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy
B Geng, J Hu, Y Li, S Feng, D Pan, L Feng… - Nature …, 2022 - nature.com
Theranostic sonosensitizers with combined sonodynamic and near infrared (NIR) imaging
modes are required for imaging guided sonodynamic therapy (SDT). It is challenging …
modes are required for imaging guided sonodynamic therapy (SDT). It is challenging …
Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives
X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …
antibiotics poses a great challenge to the effective treatment of infectious diseases …
One-step integration of tumor microenvironment-responsive calcium and copper peroxides nanocomposite for enhanced chemodynamic/ion-interference therapy
B Liu, Y Bian, S Liang, M Yuan, S Dong, F He, S Gai… - ACS …, 2021 - ACS Publications
Recently, various metal peroxide nanomaterials have drawn increasing attention as an
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …
Nanozymes: versatile platforms for cancer diagnosis and therapy
X Zhang, X Chen, Y Zhao - Nano-Micro Letters, 2022 - Springer
Natural enzymes usually suffer from high production cost, ease of denaturation and
inactivation, and low yield, making them difficult to be broadly applicable. As an emerging …
inactivation, and low yield, making them difficult to be broadly applicable. As an emerging …
Architecture of Vanadium‐Based MXene Dysregulating Tumor Redox Homeostasis for Amplified Nanozyme Catalytic/Photothermal Therapy
R Zhao, Y Zhu, L Feng, B Liu, Y Hu, H Zhu… - Advanced …, 2024 - Wiley Online Library
Taking the significance of the special microenvironment for tumor cell survival into account,
disrupting tumor redox homeostasis is highly prospective for improving therapeutic efficacy …
disrupting tumor redox homeostasis is highly prospective for improving therapeutic efficacy …
Strategies for enhancing cancer chemodynamic therapy performance
D Jana, Y Zhao - Exploration, 2022 - Wiley Online Library
Chemodynamic therapy (CDT) has emerged to be a frontrunner amongst reactive oxygen
species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor …
species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor …
A cascade nanozyme with amplified sonodynamic therapeutic effects through comodulation of hypoxia and immunosuppression against cancer
The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …