Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives

X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …

Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances

C Jia, Y Guo, FG Wu - Small, 2022 - Wiley Online Library
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy

B Geng, J Hu, Y Li, S Feng, D Pan, L Feng… - Nature …, 2022 - nature.com
Theranostic sonosensitizers with combined sonodynamic and near infrared (NIR) imaging
modes are required for imaging guided sonodynamic therapy (SDT). It is challenging …

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

“Three‐in‐one” nanozyme composite for augmented cascade catalytic tumor therapy

Y Cheng, YD **a, YQ Sun, Y Wang… - Advanced Materials, 2024 - Wiley Online Library
Cascade catalytic reaction exhibits simple procedure and high efficiency, such as that from
the orderly assembly of different enzymes in biological systems. Mimicking of the natural …

Single atom catalysts remodel tumor microenvironment for augmented sonodynamic immunotherapy

B Geng, J Hu, X He, Z Zhang, J Cai, D Pan… - Advanced …, 2024 - Wiley Online Library
The immunosuppressive tumor microenvironment (TME) is a huge hurdle in immunotherapy.
Sono‐immunotherapy is a new treatment modality that can reverse immunosuppressive …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Deep insight of design, mechanism, and cancer theranostic strategy of nanozymes

L Yang, S Dong, S Gai, D Yang, H Ding, L Feng… - Nano-Micro Letters, 2024 - Springer
Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007, nanozymes are
becoming the promising substitutes for natural enzymes due to their advantages of high …

Nanozymes: versatile platforms for cancer diagnosis and therapy

X Zhang, X Chen, Y Zhao - Nano-Micro Letters, 2022 - Springer
Natural enzymes usually suffer from high production cost, ease of denaturation and
inactivation, and low yield, making them difficult to be broadly applicable. As an emerging …

Architecture of Vanadium‐Based MXene Dysregulating Tumor Redox Homeostasis for Amplified Nanozyme Catalytic/Photothermal Therapy

R Zhao, Y Zhu, L Feng, B Liu, Y Hu, H Zhu… - Advanced …, 2024 - Wiley Online Library
Taking the significance of the special microenvironment for tumor cell survival into account,
disrupting tumor redox homeostasis is highly prospective for improving therapeutic efficacy …