Ischemic stroke is the most common type of cerebrovascular disease with high disability and
mortality rates, which severely burdens patients, their families, and society. At present …

Beta-blockers are widely prescribed for the treatment of a variety of cardiovascular
pathologies. Compared to traditional beta-adrenergic antagonists, beta-blockers of the new …

S100A1 is a small Ca2+-binding protein expressed in the myocardium and blood vessels
that is downregulated in the diseased heart and plays a role in the regulation of cardiac …

Medications used to control hypertension in pregnancy also improve trophoblast and
endothelial cellular interaction in vitro. Tumour necrosis factor‐α (TNF‐α) inhibits trophoblast …

Proanthocyanidins are condensed tannins present in fruits, vegetables, and flowers,
consumed in the human diet. These compounds are believed to decrease coronary heart …

INTRODUCTION: The vascular endothelium plays a major role in the control of arterial tone;
however, its role in venous tissues is less clear. The purpose of this study was to determine …

In this crossover study, we investigated the influence of inorganic nitrate (NO 3−)
supplementation on venous volume and compliance in the resting forearm and calf. Twenty …

This study evaluates the vasorelaxant and antihypertensive effects of the aqueous extract
from the stem bark of M. africana (AEMA). AEMA was tested in vitro on intact or endothelium …

The potential role of calcimimetics as vasculotropic agents has been suggested since the
discovery that calcium sensing receptors (CaSRs) are expressed in cardiovascular tissues …

Objectives Purine nucleotides play a central role in signal transduction events initiated at the
cell membrane. The NO–cGMP–cGK pathway, in particular, mediates events involving NOS …