The coexistence of amyloid-β (Aβ) and human islet amyloid polypeptide (hIAPP) in the brain
and pancreas is associated with an increased risk of Alzheimer's disease (AD) and type 2 …

The correct functioning of organisms heavily relies on proteins and RNAs, which hold
significant roles in governing biological pathways and mechanisms from a molecular …

Human calcitonin (hCT) regulates calcium–phosphorus metabolism, but its amyloid
aggregation disrupts physiological activity, increases thyroid carcinoma risk, and hampers …

The aggregation of amyloid-β (Aβ) into amyloid fibrils is the major pathological hallmark of
Alzheimer's disease (AD). Aβ fibrils can adopt a variety of morphologies, the relative …

Medin amyloid, prevalent in the vessel walls of 97% of individuals over 50, contributes to
arterial stiffening and cerebrovascular dysfunction, yet our understanding of its aggregation …

This study examines the remarkable effectiveness of Withaferin-A (WA), a withanolide
obtained from Withania somnifera (Ashwagandha), in encountering the mortiferous breast …

Emerging evidence suggests that physiological C-terminal truncation of α-synuclein (αS)
plays a critical role in regulating liquid–liquid phase separation and promoting amyloid …

Human calcitonin (hCT) is a peptide hormone that regulates calcium homeostasis, but its
abnormal aggregation can disrupt physiological functions and increase the risk of medullary …

Pathological aggregation of essentially dissociated Transthyretin (TTR) monomer proteins,
driven by misfolding and self-interaction, is associated with Transthyretin amyloidosis …

Aberrant aggregation of amyloid-β (Aβ) and islet amyloid polypeptide (IAPP) into amyloid
fibrils underlies the pathogenesis of Alzheimer's disease (AD) and type 2 diabetes (T2D) …