AI in the clinical management of GA: a novel therapeutic universe requires novel tools
GS Reiter, J Mai, S Riedl, K Birner, S Frank… - Progress in Retinal and …, 2024 - Elsevier
Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
The role of the retinal vasculature in age-related macular degeneration: a spotlight on OCTA
Age-related macular degeneration (AMD) remains a disease with high morbidity and an
incompletely understood pathophysiological mechanism. The ocular blood supply has been …
incompletely understood pathophysiological mechanism. The ocular blood supply has been …
Automated deep learning-based AMD detection and staging in real-world OCT datasets (PINNACLE study report 5)
Real-world retinal optical coherence tomography (OCT) scans are available in abundance
in primary and secondary eye care centres. They contain a wealth of information to be …
in primary and secondary eye care centres. They contain a wealth of information to be …
Deep survival modeling of longitudinal retinal OCT volumes for predicting the onset of atrophy in patients with intermediate AMD
In patients with age-related macular degeneration (AMD), the risk of progression to late
stages is highly heterogeneous, and the prognostic imaging biomarkers remain unclear. We …
stages is highly heterogeneous, and the prognostic imaging biomarkers remain unclear. We …
[HTML][HTML] Systematic review of prognostic factors associated with progression to late age-related macular degeneration: Pinnacle study report 2
There is a need to identify accurately prognostic factors that determine the progression of
intermediate to late-stage age-related macular degeneration (AMD). Currently, clinicians …
intermediate to late-stage age-related macular degeneration (AMD). Currently, clinicians …
Topographic and quantitative correlation of structure and function using deep learning in subclinical biomarkers of intermediate age-related macular degeneration
To examine the morphological impact of deep learning (DL)-quantified biomarkers on point-
wise sensitivity (PWS) using microperimetry (MP) and optical coherence tomography (OCT) …
wise sensitivity (PWS) using microperimetry (MP) and optical coherence tomography (OCT) …
3DTINC: Time-Equivariant Non-Contrastive Learning for Predicting Disease Progression from Longitudinal OCTs
Self-supervised learning (SSL) has emerged as a powerful technique for improving the
efficiency and effectiveness of deep learning models. Contrastive methods are a prominent …
efficiency and effectiveness of deep learning models. Contrastive methods are a prominent …
[HTML][HTML] Deep Learning–Based Clustering of OCT Images for Biomarker Discovery in Age-Related Macular Degeneration (PINNACLE Study Report 4)
Purpose We introduce a deep learning–based biomarker proposal system for the purpose of
accelerating biomarker discovery in age-related macular degeneration (AMD). Design …
accelerating biomarker discovery in age-related macular degeneration (AMD). Design …
[HTML][HTML] Generalizable deep learning for the detection of incomplete and complete retinal pigment epithelium and outer retinal atrophy: a Macustar report
Purpose: The purpose of this study was to develop a deep learning algorithm for detecting
and quantifying incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) and …
and quantifying incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) and …
Advanced therapy medicinal products for age-related macular degeneration; scaffold fabrication and delivery methods
Retinal degenerative diseases such as age-related macular degeneration (AMD) represent
a leading cause of blindness, resulting in permanent damage to retinal cells that are …
a leading cause of blindness, resulting in permanent damage to retinal cells that are …