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[HTML][HTML] Tenofovir, another inexpensive, well-known and widely available old drug repurposed for SARS-COV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading
worldwide with different clinical manifestations. Age and comorbidities may explain severity …
worldwide with different clinical manifestations. Age and comorbidities may explain severity …
Covalent organic frameworks and metal-organic frameworks against pathogenic viruses and antibiotic-resistant bacteria: Diagnostic and therapeutic applications
Antimicrobial resistance and antiviral infections statistics show that the number of global
cases has been exponentially increasing; thus there is an unmet need for develo** …
cases has been exponentially increasing; thus there is an unmet need for develo** …
Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto …
Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …
The impact of D614G mutation of SARS-COV-2 on the efficacy of anti-viral drugs: A comparative molecular docking and molecular dynamics study
D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has
altered some crucial characteristics of coronaviruses, such as rate of infection and binding …
altered some crucial characteristics of coronaviruses, such as rate of infection and binding …
Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound
A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …
the essential proteins associated with PCa could be a promising method for cancer …
A biochemistry‐oriented drug design: synthesis, anticancer activity, enzymes inhibition, molecular docking studies of novel 1, 2, 4-triazole derivatives
K Yuriy, G Kusdemir, P Volodymyr… - Journal of …, 2024 - Taylor & Francis
In this study, we researched the reactions of 5-(5-bromofuran-2-yl)-4-methyl-1, 2, 4-triazole-3-
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …
Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation
B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods
A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
A complete investigation to understand the pathways that could be affected by glycyrrhizin
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method
Drug development for cancer treatment is a complex process that requires special efforts.
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …
A new generalized pole clustering-based model reduction technique and its application for design of controllers
AK Prajapati, R Prasad - Circuits, Systems, and Signal Processing, 2022 - Springer
A new model diminution technique is proposed for the reduction of complexity of higher
order linear dynamical systems. In this proposed method, a generalized pole clustering …
order linear dynamical systems. In this proposed method, a generalized pole clustering …