[HTML][HTML] Tenofovir, another inexpensive, well-known and widely available old drug repurposed for SARS-COV-2 infection

I Zanella, D Zizioli, F Castelli, E Quiros-Roldan - Pharmaceuticals, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading
worldwide with different clinical manifestations. Age and comorbidities may explain severity …

Covalent organic frameworks and metal-organic frameworks against pathogenic viruses and antibiotic-resistant bacteria: Diagnostic and therapeutic applications

MH Nematollahi, E Mostafavi, S Iravani - Journal of Environmental …, 2023 - Elsevier
Antimicrobial resistance and antiviral infections statistics show that the number of global
cases has been exponentially increasing; thus there is an unmet need for develo** …

Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound

A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …

A biochemistry‐oriented drug design: synthesis, anticancer activity, enzymes inhibition, molecular docking studies of novel 1, 2, 4-triazole derivatives

K Yuriy, G Kusdemir, P Volodymyr… - Journal of …, 2024 - Taylor & Francis
In this study, we researched the reactions of 5-(5-bromofuran-2-yl)-4-methyl-1, 2, 4-triazole-3-
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …

Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation

A Poustforoosh, S Faramarz, M Negahdaripour… - Scientific Reports, 2023 - nature.com
B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …

Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods

A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
A complete investigation to understand the pathways that could be affected by glycyrrhizin
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …

In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method

A Poustforoosh, S Faramarz, MH Nematollahi… - Computers in Biology …, 2022 - Elsevier
Drug development for cancer treatment is a complex process that requires special efforts.
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …

A new generalized pole clustering-based model reduction technique and its application for design of controllers

AK Prajapati, R Prasad - Circuits, Systems, and Signal Processing, 2022 - Springer
A new model diminution technique is proposed for the reduction of complexity of higher
order linear dynamical systems. In this proposed method, a generalized pole clustering …