Amorphous solid dispersions: role of the polymer and its importance in physical stability and in vitro performance
Amorphous solid dispersions stabilized by one or more polymer (s) have been widely used
for delivering amorphous drugs with poor water solubilities, and they have gained great …
for delivering amorphous drugs with poor water solubilities, and they have gained great …
Co-amorphous Drug Delivery Systems: a Review of Physical Stability, In Vitro and In Vivo Performance
Over the past few decades, co-amorphous solids have been used as a promising approach
for delivering poorly water-soluble drugs. Co-amorphous solids, comprising …
for delivering poorly water-soluble drugs. Co-amorphous solids, comprising …
Improving physicochemical properties and pharmacological activities of ternary co-amorphous systems
X Fang, Y Hu, G Yang, W Shi, S Lu, Y Cao - European Journal of …, 2022 - Elsevier
The formation of co-amorphous by combining low molecular weight compounds with drugs
is a relatively new technology in the pharmaceutical field, which can significantly improve …
is a relatively new technology in the pharmaceutical field, which can significantly improve …
Role of supercritical CO2 impregnation variables on β-carotene loading into corn starch aerogel particles
Abstract β-carotene is a natural dye with antioxidant and provitamin A activities, which has
essential roles in human health. However, its direct use in food products is unviable since it …
essential roles in human health. However, its direct use in food products is unviable since it …
Hydroxypropyl-β-cyclodextrin-based solid dispersed granules: A prospective alternative to conventional solid dispersion
The purpose of the present study was to develop hydroxypropyl-β-cyclodextrin (HP-β-CD)-
based solid dispersed granules as a superior system to solid dispersion. The solid …
based solid dispersed granules as a superior system to solid dispersion. The solid …
Introduction to Pharmaceutical Co-amorphous Systems Using a Green Co-milling Technique
The concept of co-amorphous systems is introduced in an integrated laboratory experiment,
designed for advanced chemistry students, using solvent-free, environmentally friendly …
designed for advanced chemistry students, using solvent-free, environmentally friendly …
Formulation of nitrendipine/hydroxypropyl-β-cyclodextrin inclusion complex as a drug delivery system to enhance the solubility and bioavailability by supercritical fluid …
B Liang, J Hao, N Zhu, L Han, L Song, H Hong - European Polymer Journal, 2023 - Elsevier
In this study, the solution enhanced dispersion by supercritical fluids (SEDS) technology was
applied to prepare inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD) as …
applied to prepare inclusion complex with hydroxypropyl-β-cyclodextrin (HP-β-CD) as …
Fused Deposition Modelling 3D printing and solubility improvement of BCS II and IV active ingredients–A narrative review
A Roche, NM Sanchez-Ballester, B Bataille… - Journal of Controlled …, 2024 - Elsevier
In the field of pharmaceutical research and development, Fused Deposition Modelling
(FDM) 3D printing (3DP) has aroused growing interest within the last ten years. The use of …
(FDM) 3D printing (3DP) has aroused growing interest within the last ten years. The use of …
Evaluating spray gelation and spray freeze drying as the granulation method to prepare oral tablets of amorphous drug nanoplex
Amorphous drug nanoplex represents one of the most promising solubility enhancement
strategies of poorly-soluble drugs. Solubility enhancement capability of nanoplex hitherto …
strategies of poorly-soluble drugs. Solubility enhancement capability of nanoplex hitherto …
Mesoporous Drug Delivery System: From Physical Properties of Drug in Solid State to Controlled Release
Y Wang, F Li, J **n, J Xu, G Yu, Q Shi - Molecules, 2023 - mdpi.com
Mesoporous materials, which exhibit great potential in the control of polymorphs and
delivery of poorly water-soluble drugs, have obtained considerable attention in the field of …
delivery of poorly water-soluble drugs, have obtained considerable attention in the field of …