Metal-organic frameworks (MOF) have been studied for infinite applications. Among these,
anticancer therapy has surely attracted great interest due to the intrinsic characteristics of …

Conspectus Immune checkpoint blockade (ICB) therapy elicits antitumor response by
inhibiting immune suppressor components, including programmed cell death protein 1 and …

The occurrence of colorectal cancer (CRC) has been rising expeditiously and anticipated
that 2.4 million new occasions of CRC will be detected yearly around the world until the year …

The growth and development of cancer are directly correlated to the suppression of the
immune system. A major breakthrough in cancer immunotherapy depends on various …

Although the ever-increasing number of cancer patients pose substantial challenges
worldwide, finding a treatment with the highest response rate and the lowest number of side …

V-domain Ig suppressor of T cell activation (VISTA) is a novel checkpoint regulator with
limited homology to other B7 family members. The constitutive expression of VISTA on both …

Immune system has critical roles in fighting against several diseases like cancer. Cancer
cells evolve several ways to escape from the immune system to remain alive and trigger new …

There are numerous investigated factors that limit brain cancer treatment efficacy such as
ability of prescribed therapy to cross the blood-brain barrier (BBB), tumor specific delivery of …

Within the last decade, the introduction of checkpoint inhibitors proposed to boost the
patients' anti-tumor immune response has proven the efficacy of immunotherapeutic …

Gastric cancer (GC), with a heterogeneous nature, is the third leading cause of death
worldwide. Over the past few decades, stable reductions in the incidence of GC have been …