[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application

ME Ladd, P Bachert, M Meyerspeer, E Moser… - Progress in nuclear …, 2018 - Elsevier
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

The beginning of the end for conventional RECIST—novel therapies require novel imaging approaches

M Gerwing, K Herrmann, A Helfen… - Nature reviews Clinical …, 2019 - nature.com
Owing to improvements in our understanding of the biological principles of tumour initiation
and progression, a wide variety of novel targeted therapies have been developed …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021 - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI

J Huang, PCM van Zijl, X Han, CM Dong… - Science …, 2020 - science.org
Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A
dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) approach was …

T1ρ-weighted dynamic glucose-enhanced MR imaging in the human brain

D Paech, P Schuenke, C Koehler, J Windschuh… - Radiology, 2017 - pubs.rsna.org
Purpose To evaluate the ability to detect intracerebral regions of increased glucose
concentration at T1ρ-weighted dynamic glucose-enhanced (DGE) magnetic resonance (MR) …

Theory of chemical exchange saturation transfer MRI in the context of different magnetic fields

M Zaiss, T **, SG Kim, DF Gochberg - NMR in Biomedicine, 2022 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is a
versatile MRI method that provides contrast based on the level of molecular and metabolic …

Ultra-high-field MRI in the diagnosis and management of gliomas: a systematic review

A Shaffer, SS Kwok, A Naik, AT Anderson… - Frontiers in …, 2022 - frontiersin.org
Importance: Gliomas, tumors of the central nervous system, are classically diagnosed
through invasive surgical biopsy and subsequent histopathological study. Innovations in …

Chemical exchange saturation transfer magnetic resonance imaging and its main and potential applications in pre-clinical and clinical studies

W Dou, CYE Lin, H Ding, Y Shen… - … imaging in medicine …, 2019 - pmc.ncbi.nlm.nih.gov
Chemical exchange saturation transfer (CEST) imaging is a novel contrast mechanism,
relying on the exchange between mobile protons in amide (-NH), amine (-NH2) and …

d‐glucose weighted chemical exchange saturation transfer (glucoCEST)‐based dynamic glucose enhanced (DGE) MRI at 3T: early experience in healthy volunteers …

X Xu, AA Sehgal, NN Yadav, J Laterra… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Dynamic glucose enhanced (DGE) MRI has shown potential for imaging glucose
delivery and blood–brain barrier permeability at fields of 7T and higher. Here, we evaluated …

Imaging of sugar‐based contrast agents using their hydroxyl proton exchange properties

L Knutsson, X Xu, PCM van Zijl… - NMR in …, 2023 - Wiley Online Library
The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …