Stroke seriously threatens human health because of its characteristics of high morbidity,
disability, recurrence, and mortality, thus representing a heavy financial and mental burden …

This review describes the most commonly used rodent models and outcome measures in
preclinical stroke research and discusses their strengths and limitations. Most models …

Acyl-CoA synthetase long-chain family member 4 (ACSL4) is an important isozyme for
polyunsaturated fatty acids (PUFAs) metabolism that dictates ferroptosis sensitivity. The role …

OBJECT Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …

Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve
functional outcome after experimental traumatic brain injury (TBI). The present study was …

Ischemic stroke is the leading cause of immortal disability and death worldwide. For
treatment in the acute phase, it is necessary to control excessive reactive oxygen species …

Background and Purpose—We tested the hypothesis that intravenous infusion of bone
marrow derived–marrow stromal cells (MSCs) enter the brain and reduce neurological …

Cerebral edema contributes significantly to morbidity and death associated with many
common neurological disorders. However, current treatment options are limited to …

Background and Purpose—Human umbilical cord blood cells (HUCBC) are rich in stem and
progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain …

Acute brain lesions induce profound alterations of the peripheral immune response
comprising the opposing phenomena of early immune activation and subsequent …