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Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
The acid sphingomyelinase/ceramide system in COVID-19
Acid sphingomyelinase (ASM) cleaves sphingomyelin into the highly lipophilic ceramide,
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …
Mortality risk among patients with COVID-19 prescribed selective serotonin reuptake inhibitor antidepressants
Importance Antidepressant use may be associated with reduced levels of several
proinflammatory cytokines suggested to be involved with the development of severe COVID …
proinflammatory cytokines suggested to be involved with the development of severe COVID …
The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial
In this study, the therapeutic efficacy of quercetin in combination with remdesivir and
favipiravir, were evaluated in severe hospitalized COVID-19 patients. Our main objective …
favipiravir, were evaluated in severe hospitalized COVID-19 patients. Our main objective …
Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …
infection has become a global pandemic due to the high viral transmissibility and …
Long COVID: complications, underlying mechanisms, and treatment strategies
FH Zadeh, DR Wilson… - Archives of microbiology & …, 2023 - pmc.ncbi.nlm.nih.gov
Long Covid is one of the most prevalent and puzzling conditions that arose with the Covid
pandemic. Covid-19 infection generally resolves within several weeks but some experience …
pandemic. Covid-19 infection generally resolves within several weeks but some experience …
Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro
Repurposing of currently available drugs is a valuable strategy to tackle the consequences
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …
Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms
We read with great interest the correspondence letters of Salles et al.[1] and Stip et al.[2],
following our multicenter observational retrospective study that showed a substantial …
following our multicenter observational retrospective study that showed a substantial …
Analysis of the impact of antidepressants and other medications on COVID-19 infection risk in a chronic psychiatric in-patient cohort
CL Clelland, K Ramiah, L Steinberg, JD Clelland - BJPsych Open, 2022 - cambridge.org
BackgroundDuring the first wave of the coronavirus disease 2019 (COVID-19) pandemic,
patients with confirmed cases in New York State accounted for roughly 25% of total US …
patients with confirmed cases in New York State accounted for roughly 25% of total US …
Overview of the potential use of fluvoxamine for COVID-19 and long COVID
K Hashimoto - Discover Mental Health, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has presented a serious worldwide threat to
public health since its emergence in late 2019. From a safety point of view, drug repurposing …
public health since its emergence in late 2019. From a safety point of view, drug repurposing …