Disruption of the intestinal epithelial barrier is a hallmark of mucosal inflammation. It
increases exposure of the immune system to luminal microbes, triggering a perpetuating …

Hematopoietic system (HS) is one of the most unique, adaptive and comprehensive
developmental systems on which various other body systems relies on. It consists of a …

Cell remodeling relies on dynamic rearrangements of cell contacts powered by the actin
cytoskeleton. The tumor suppressor adenomatous polyposis coli (APC) nucleate actin …

Hura crepitans L.(Euphorbiaceae) is a thorn-covered tree widespread in South America,
Africa and Asia which produces an irritating milky latex containing numerous secondary …

Wnt signalling is known to generate cellular asymmetry via Wnt/planar cell polarity pathway
(Wnt/PCP). Wnt/PCP acts locally (i) to orient membrane polarity and asymmetric …

Altered levels of reactive oxygen species (ROS) are recognized as one of the key factors in
mediating tumor cell survival in the tissue microenvironment, where they play a role in the …

Background Actin cytoskeleton is connected with the processes of cell proliferation and
migration in colorectal cancer (CRC). However, it is unknown how to accomplish these …

Abstract Purpose The Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel
(VCEP) was established by the International Society for Gastrointestinal Hereditary Tumours …