HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

The not-so-good, the bad and the ugly: HPV E5, E6 and E7 oncoproteins in the orchestration of carcinogenesis

O Basukala, L Banks - Viruses, 2021 - mdpi.com
Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

J Zhao, EE Lee, J Kim, R Yang, B Chamseddin… - Nature …, 2019 - nature.com
Single-stranded circular RNAs (circRNAs), generated through 'backsplicing', occur more
extensively than initially anticipated. The possible functions of the vast majority of circRNAs …

Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells

I Martinez, AS Gardiner, KF Board, FA Monzon… - Oncogene, 2008 - nature.com
Human papillomaviruses (HPVs) are involved in the pathogenesis of cancer of the cervix
(CaCx). MicroRNA (miRNA) expression analysis using Ambion (Austin, TX, USA) arrays …

The natural history of human papillomavirus infections of the mucosal epithelia

LT Chow, TR Broker, BM Steinberg - Apmis, 2010 - Wiley Online Library
Chow LT, Broker TR, Steinberg BM. The natural history of human papillomavirus infections
of the mucosal epithelia. APMIS 2010; 118: 422–449. Human papillomaviruses (HPVs) …

Regulation of cellular miRNA expression by human papillomaviruses

ZM Zheng, X Wang - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2011 - Elsevier
High-risk HPV infection leads to aberrant expression of cellular oncogenic and tumor
suppressive miRNAs. A large number of these miRNA genes are downstream targets of the …

Human papillomavirus: gene expression, regulation and prospects for novel diagnostic methods and antiviral therapies

SV Graham - Future microbiology, 2010 - Taylor & Francis
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive
tumors. A subset of these viruses termed 'high risk 'infect the cervix where persistent …

[HTML][HTML] Cellular transformation by human papillomaviruses: lessons learned by comparing high-and low-risk viruses

AJ Klingelhutz, A Roman - Virology, 2012 - Elsevier
The oncogenic potential of papillomaviruses (PVs) has been appreciated since the 1930s
yet the mechanisms of virally-mediated cellular transformation are still being revealed …

Regulation of human papillomavirus gene expression by splicing and polyadenylation

C Johansson, S Schwartz - Nature reviews Microbiology, 2013 - nature.com
Human papillomaviruses (HPVs) are small DNA tumour viruses that are present in more
than 99% of all cervical cancers. The ability of these viruses to cause disease is partly …

Human papillomavirus type 16 E6* induces oxidative stress and DNA damage

VM Williams, M Filippova, V Filippov, KJ Payne… - Journal of …, 2014 - Am Soc Microbiol
High-risk types of human papillomavirus (HPV) are the causative agents of virtually all cases
of cervical cancer and a significant proportion of other anogenital cancers, as well as both …