Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times.
They have enjoyed over 30 years of clinical usage and become essential tools in the …

Antibiotics target energy-consuming processes. As such, perturbations to bacterial metabolic
homeostasis are significant consequences of treatment. Here, we describe three postulates …

Bactericidal antibiotics can cause metabolic perturbations that contribute to antibiotic-
induced lethality. The molecular mechanism underlying these downstream effects remains …

Considering the variations in burns depending on the circumstances that caused them, the
need for personalized medicine and care for burn victims is vital to ensure that optimal …

Fluoroquinolones remain one of the most important kind of antibacterial agents used
nowadays. The emergence of more virulent and resistant strains of bacteria by the …

In recent times, 3D printing has been gaining traction as a fabrication platform for
customizable drug dosages as a form of personalized medicine. While this has been …

New antibacterial 3-(aminothiazolyl) quinolones (ATQs) were designed and efficiently
synthesized to counteract the growing multidrug resistance in animal husbandry. Bioactive …

Unique benzopyridone cyanoacetates (BCs) as new type of promising broad-spectrum
antibacterial candidates were discovered with large potential to combat the lethal multidrug …

The widespread use of levofloxacin (LEV) and oxytetracycline (OTC) in hospitals and farms
inevitably contributes to water pollution through waste disposal processes, municipal …

Antimicrobial resistance has become a growing public health concern in recent decades,
demanding a search for new effective treatments. Therefore, this study aimed to elucidate …