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Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …
Endothelial to mesenchymal transition: role in physiology and in the pathogenesis of human diseases
S Piera-Velazquez, SA Jimenez - Physiological reviews, 2019 - journals.physiology.org
Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …
Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …
The safety of ingested caffeine: a comprehensive review
Caffeine is the most widely consumed psychoactive drug in the world. Natural sources of
caffeine include coffee, tea, and chocolate. Synthetic caffeine is also added to products to …
caffeine include coffee, tea, and chocolate. Synthetic caffeine is also added to products to …
Human nitric oxide synthase—Its functions, polymorphisms, and inhibitors in the context of inflammation, diabetes and cardiovascular diseases
M Król, M Kepinska - International Journal of Molecular Sciences, 2020 - mdpi.com
In various diseases, there is an increased production of the free radicals needed to carry out
certain physiological processes but their excessive amounts can cause oxidative stress and …
certain physiological processes but their excessive amounts can cause oxidative stress and …
Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration
S Stegen, N Van Gastel, G Carmeliet - Bone, 2015 - Elsevier
Bone has the unique capacity to heal without the formation of a fibrous scar, likely because
several of the cellular and molecular processes governing bone healing recapitulate the …
several of the cellular and molecular processes governing bone healing recapitulate the …
Coaxial cell printing of freestanding, perfusable, and functional in vitro vascular models for recapitulation of native vascular endothelium pathophysiology
Abstract 3D printing technology is used to produce channels within hydrogels followed by
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …
[HTML][HTML] Lipopolysaccharide signaling in endothelial cells
SM Dauphinee, A Karsan - Laboratory investigation, 2006 - Elsevier
Sepsis is the systemic immune response to severe bacterial infection. The innate immune
recognition of bacterial and viral products is mediated by a family of transmembrane …
recognition of bacterial and viral products is mediated by a family of transmembrane …
Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease
P Grammas - Journal of neuroinflammation, 2011 - Springer
Alzheimer's disease (AD) is an age-related disorder characterized by progressive cognitive
decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 …
decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 …
An introductory review of cell mechanobiology
JHC Wang, BP Thampatty - Biomechanics and modeling in …, 2006 - Springer
Mechanical loads induce changes in the structure, composition, and function of living
tissues. Cells in tissues are responsible for these changes, which cause physiological or …
tissues. Cells in tissues are responsible for these changes, which cause physiological or …