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Etiology and pathogenesis of late-onset Alzheimer's disease
BJ Balin, AP Hudson - Current allergy and asthma reports, 2014 - Springer
Alzheimer's disease (AD) is a neurodegenerative condition that occurs in two forms, an early-
onset form that is genetically determined and a far more common late-onset form that is not …
onset form that is genetically determined and a far more common late-onset form that is not …
Membrane damage induced by amyloid beta and a potential link with neuroinflammation
It is well accepted that cortical and hippocampal synaptic densities are reduced in
Alzheimer's disease (AD). These alterations in neuronal networking occur at the very onset …
Alzheimer's disease (AD). These alterations in neuronal networking occur at the very onset …
The citrus flavonoid, nobiletin inhibits neuronal inflammation by preventing the activation of NF-κB
T Murata, S Ishiwa, X Lin, Y Nakazawa, K Tago… - Neurochemistry …, 2023 - Elsevier
Abstract Nobiletin (5, 6, 7, 8, 3′, 4′-hexamethoxyflavone) is one of the flavonoids found in
shikuwasa, a popular citrus fruit in Okinawa, Japan. It exerts various pharmacological …
shikuwasa, a popular citrus fruit in Okinawa, Japan. It exerts various pharmacological …
ZnO Nanoflower petals mediated amyloid degradation-An in vitro electrokinetic potential approach
An electrokinetic potential (ζ-potential) based approach was introduced to address the
amyloid degradation on ZnO-nanoflower platform. The hallmark of neurodegenerative …
amyloid degradation on ZnO-nanoflower platform. The hallmark of neurodegenerative …
[HTML][HTML] Suppression of neuroinflammation by coffee component pyrocatechol via inhibition of NF-κB in microglia
T Murata, K Tago, K Miyata, Y Moriwaki… - International journal of …, 2023 - mdpi.com
According to numerous studies, it has been epidemiologically suggested that habitual coffee
intake seems to prevent the onset of neurodegenerative diseases. In this study, we …
intake seems to prevent the onset of neurodegenerative diseases. In this study, we …
Pharmacological approaches for Alzheimer's disease: neurotransmitter as drug targets
Alzheimer's disease (AD) is the most common CNS disorder occurring worldwide. There is
neither proven effective prevention for AD nor a cure for patients with this disorder. Hence …
neither proven effective prevention for AD nor a cure for patients with this disorder. Hence …
Exploring the role of P2X receptors in Alzheimer's disease
Several studies have pointed to soluble oligomers of beta amyloid peptide (SOAβ) as the
principal neurotoxic agents responsible for the generation of synaptotoxic events that can …
principal neurotoxic agents responsible for the generation of synaptotoxic events that can …
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease …
Machado–Joseph disease or spinocerebellar ataxia type 3 is an inherited
neurodegenerative disease associated with an abnormal glutamine over-repetition within …
neurodegenerative disease associated with an abnormal glutamine over-repetition within …
Neuroprotective properties of Eudesmin on a cellular model of amyloid-β peptide toxicity
C Castillo, G Bravo-Arrepol, A Wendt… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by
progressive cognitive impairment and memory loss. One of the hallmarks in AD is amyloid-ß …
progressive cognitive impairment and memory loss. One of the hallmarks in AD is amyloid-ß …
Ibuprofen targets neuronal pentraxins expresion and improves cognitive function in mouse model of AlCl3-induced neurotoxicity
A Jamil, A Mahboob, T Ahmed - Experimental and …, 2016 - spandidos-publications.com
Aluminum is known to exert neurotoxic effects associated with various neurodegenerative
disorders, including Alzheimer's disease (AD). Ibuprofen is a well-known non-steroidal anti …
disorders, including Alzheimer's disease (AD). Ibuprofen is a well-known non-steroidal anti …