Respiratory syncytial virus: infection, detection, and new options for prevention and treatment
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …
in North America and one of the leading causes of death of infants less than 1 year of age …
Cell death in the lung: the apoptosis–necroptosis axis
Regulated cell death is a major mechanism to eliminate damaged, infected, or superfluous
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …
The airway epithelium: more than just a structural barrier
A Tam, S Wadsworth, D Dorscheid… - Therapeutic …, 2011 - journals.sagepub.com
The mammalian airway is lined by a variety of specialized epithelial cells that not only serve
as a physical barrier but also respond to environment-induced damage through the release …
as a physical barrier but also respond to environment-induced damage through the release …
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research
CE Stewart, EE Torr, NH Mohd Jamili… - Journal of …, 2012 - Wiley Online Library
The aim of the current study was to evaluate primary (human bronchial epithelial cells,
HBEC) and non‐primary (Calu‐3, BEAS‐2B, BEAS‐2B R1) bronchial epithelial cell culture …
HBEC) and non‐primary (Calu‐3, BEAS‐2B, BEAS‐2B R1) bronchial epithelial cell culture …
Strategies targeting the IL-4/IL-13 axes in disease
RD May, M Fung - Cytokine, 2015 - Elsevier
Abstract IL-4 and IL-13 are pleiotropic Th2 cytokines produced by a wide variety of different
cell types and responsible for a broad range of biology and functions. Physiologically, Th2 …
cell types and responsible for a broad range of biology and functions. Physiologically, Th2 …
Structural and functional variations in human bronchial epithelial cells cultured in air-liquid interface using different growth media
C Leung, SJ Wadsworth, SJ Yang… - American Journal of …, 2020 - journals.physiology.org
The human bronchial epithelium is an important barrier tissue that is damaged or
pathologically altered in various acute and chronic respiratory conditions. To represent the …
pathologically altered in various acute and chronic respiratory conditions. To represent the …
Macrophages in allergic asthma: fine-tuning their pro-and anti-inflammatory actions for disease resolution
AP Moreira, CM Hogaboam - Journal of Interferon & Cytokine …, 2011 - liebertpub.com
Macrophages exert prominent effects in the defense of the respiratory tract from airborne
pathogens. These cells are specialized to recognize, phagocytose, and destroy these …
pathogens. These cells are specialized to recognize, phagocytose, and destroy these …
[HTML][HTML] IL-13 stimulates proliferation and expression of mucin and immunomodulatory genes in cultured conjunctival goblet cells
Purpose.: To investigate the effects of IL-13 on goblet cell proliferation, differentiation, and
expression of mucin and immunomodulatory genes. Methods.: Explants were excised from …
expression of mucin and immunomodulatory genes. Methods.: Explants were excised from …
Pathogenesis of severe asthma
AH Poon, DH Eidelman, JG Martin… - Clinical & …, 2012 - Wiley Online Library
Patients with severe asthma have asthma symptoms which are difficult to control, require
high dosages of medication, and continue to experience persistent symptoms, asthma …
high dosages of medication, and continue to experience persistent symptoms, asthma …
Matrix regulation of idiopathic pulmonary fibrosis: the role of enzymes
DL Clarke, AM Carruthers, T Mustelin… - Fibrogenesis & tissue …, 2013 - Springer
Repairing damaged tissues is an essential homeostatic mechanism that enables clearance
of dead or damaged cells after injury, and the maintenance of tissue integrity. However …
of dead or damaged cells after injury, and the maintenance of tissue integrity. However …