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Glycogen synthase kinases: Moonlighting proteins with theranostic potential in cancer
Abstract Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase is an archetypal
multifunctional moonlighting protein involved in diverse cellular processes including …
multifunctional moonlighting protein involved in diverse cellular processes including …
The role of ubiquitination and deubiquitination in the regulation of cell junctions
Maintenance of cell junctions plays a crucial role in the regulation of cellular functions
including cell proliferation, permeability, and cell death. Disruption of cell junctions is …
including cell proliferation, permeability, and cell death. Disruption of cell junctions is …
[HTML][HTML] Potential anti-cancer properties of malvidin and its glycosides: Evidence from in vitro and in vivo studies
R Sood, HK Choi, HJ Lee - Journal of Functional Foods, 2024 - Elsevier
Malvidin and its glycosides have been studied for their anti-carcinogenic potential in various
forms of cancer, however the in-depth review for malvidin and its glycosides in in vitro and in …
forms of cancer, however the in-depth review for malvidin and its glycosides in in vitro and in …
New insights into the role of GSK-3β in the brain: from neurodegenerative disease to tumorigenesis
S Lai, P Wang, J Gong, S Zhang - PeerJ, 2023 - peerj.com
Abstract Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase widely expressed
in various tissues and organs. Unlike other kinases, GSK-3 is active under resting conditions …
in various tissues and organs. Unlike other kinases, GSK-3 is active under resting conditions …
COVID-19. Pandemic surgery guidance
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
3, 3′-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through …
P Zhu, H Yu, K Zhou, Y Bai, R Qi, S Zhang - Journal of Experimental & …, 2020 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive
tumors in the world. Aryl hydrocarbon receptor (AHR) has been reported to promote tumor …
tumors in the world. Aryl hydrocarbon receptor (AHR) has been reported to promote tumor …
Alpinetin improves intestinal barrier homeostasis via regulating AhR/suv39h1/TSC2/mTORC1/autophagy pathway
Y Miao, Q Lv, S Qiao, L Yang, Y Tao, W Yan… - Toxicology and Applied …, 2019 - Elsevier
The injury of intestinal epithelial barrier is considered as the key pathophysiological process
in response to gastrointestinal infection and inflammation, and plays an important role in the …
in response to gastrointestinal infection and inflammation, and plays an important role in the …
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis
S Nothdurft, C Thumser-Henner, F Breitenbücher… - Oncogenesis, 2020 - nature.com
Lung cancer mortality largely results from metastasis. Despite curative surgery many
patients with early-stage non-small cell lung cancer ultimately succumb to metastatic …
patients with early-stage non-small cell lung cancer ultimately succumb to metastatic …
p23 protects the human aryl hydrocarbon receptor from degradation via a heat shock protein 90-independent mechanism
B Pappas, Y Yang, Y Wang, K Kim, HJ Chung… - Biochemical …, 2018 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-activated signaling molecule which is
involved in diverse biological functions ranging from cancer metastasis to immune …
involved in diverse biological functions ranging from cancer metastasis to immune …
[HTML][HTML] Regulation of soluble E-cadherin signaling in non-small-cell lung cancer cells by nicotine, BDNF, and β-adrenergic receptor ligands
R Ray, S Goel, H Al Khashali, B Darweesh, B Haddad… - Biomedicines, 2023 - mdpi.com
The ectodomain of the transmembrane protein E-cadherin can be cleaved and released in a
soluble form referred to as soluble E-cadherin, or sE-cad, accounting for decreased E …
soluble form referred to as soluble E-cadherin, or sE-cad, accounting for decreased E …