Malaria, in particular infection with P. falciparum (the most lethal of the human malaria
parasite species, responsible for nearly one million deaths every year), is one of the most …

A simple, primary amine bearing a C10H15 alkyl residue was found to display potent anti-
Influenza A properties in 1964. 1 Soon thereafter, antiviral activity of this amine was found …

The quinoline scaffold is prevalent in a variety of pharmacologically active synthetic and
natural compounds. The discovery of chloroquine, the most famous drug containing this …

Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

Malaria has been teasing human populations from a long time. Presently, several classes of
antimalarial drugs are available in market, but the issues of toxicity, lower efficacy and the …

Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …

A short history of hybrid molecules based on aminoquinolines gave interesting and
important information useful for organic and medicinal chemistry, which are deeply involved …

Amongst several communicable diseases (CDs), malaria is one of the deadliest parasitic
disease all over the world, particularly in African and Asian countries. To curb this menace …

Abstract A series of 4-amino-7-chloroquinoline derivatives were synthesized by the reaction
of 4, 7-dichloro-quinoline with the corresponding diamine and then with propargyl bromide …

Upon photoirradiation of o-alkynylaryl isocyanides in the presence of iodine, the
intramolecular cyclization of o-alkynylaryl isocyanides proceeds to afford the corresponding …