Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

Secretion of RNAs in extracellular vesicles is a newly recognized form of intercellular
communication. A potential regulatory protein for microRNA (miRNA) secretion is the critical …

Trafficking of biological material across membranes is an evolutionary conserved
mechanism and is part of any normal cell homeostasis. Such transport is composed of …

Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

The prevalence of overweight and obesity in developed and develo** countries has
greatly increased the risk of insulin resistance and type 2 diabetes mellitus. It is evident from …

The development of human cancers is a multistep process in which normal cells acquire
characteristics that ultimately lead to their conversion into cancer cells. Many obstacles must …