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Cardiac energy metabolism in heart failure
Alterations in cardiac energy metabolism contribute to the severity of heart failure. However,
the energy metabolic changes that occur in heart failure are complex and are dependent not …
the energy metabolic changes that occur in heart failure are complex and are dependent not …
Branched-chain amino acids in cardiovascular disease
Research conducted in the past 15 years has yielded crucial insights that are resha** our
understanding of the systems physiology of branched-chain amino acid (BCAA) metabolism …
understanding of the systems physiology of branched-chain amino acid (BCAA) metabolism …
Myocardial metabolomics of human heart failure with preserved ejection fraction
Background: The human heart primarily metabolizes fatty acids, and this decreases as
alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF). Patients with …
alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF). Patients with …
Signaling pathways in obesity: mechanisms and therapeutic interventions
X Wen, B Zhang, B Wu, H ** of human cardiac fuel use is lacking. We used metabolomics on blood from artery …
Metabolism of amino acids in cancer
Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The
uptake and metabolism of amino acids are aberrantly upregulated in many cancers that …
uptake and metabolism of amino acids are aberrantly upregulated in many cancers that …
Targeting mitochondria-inflammation circuit by β-hydroxybutyrate mitigates HFpEF
Y Deng, M **e, Q Li, X Xu, W Ou, Y Zhang… - Circulation …, 2021 - ahajournals.org
Rationale: Over 50% of patients with heart failure have preserved ejection fraction (HFpEF),
rather than reduced ejection fraction. Complexity of its pathophysiology and the lack of …
rather than reduced ejection fraction. Complexity of its pathophysiology and the lack of …