Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …

Breast cancer represents a highly heterogeneous disease comprised by several subtypes
with distinct histological features, underlying molecular etiology and clinical behaviors. It is …

Normalization of the tumor microenvironment by selectively targeting components of the
tumor extracellular matrix has been recently proposed to have the potential to decompress …

Background Breast cancer (BC) is the most common type of cancer in women and the
second cause of cancer-related mortality world-wide. The majority of BC-related deaths is …

Lung cancer remains the leading cause of cancer‐related death due to poor treatment
responses and resistance arising from tumour heterogeneity. Here, we show that adverse …

Abstract Interleukin 13 receptor alpha 2 (IL13Rα2) is increasingly recognized as a relevant
player in cancer invasion and metastasis. Despite being initially considered a decoy …

Despite the important role that mechanical forces play in tumor growth and therapy, the
contribution of swelling to tumor mechanopathology remains unexplored. Tumors rich in …

Interleukin-13 receptor subunit alpha-2 (IL-13Rα2, CD213A), a high-affinity membrane
receptor of the anti-inflammatory Th2 cytokine IL-13, is overexpressed in a variety of solid …

Accumulation of mechanical stresses during cancer progression can induce blood and
lymphatic vessel compression, creating hypo-perfusion, hypoxia and interstitial hypertension …

Biomarkers are an integral part of cancer management due to their use in risk assessment,
screening, differential diagnosis, prognosis, prediction of response to treatment, and …