Osteosarcoma

HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Ewing sarcoma—diagnosis, treatment, clinical challenges and future perspectives

SK Zöllner, JF Amatruda, S Bauer, S Collaud… - Journal of clinical …, 2021 - mdpi.com
Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …

[HTML][HTML] Molecular biology of osteosarcoma

AM Czarnecka, K Synoradzki, W Firlej, E Bartnik… - Cancers, 2020 - mdpi.com
Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents
and the third most frequent in adults. Many inherited germline mutations are responsible for …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

PG Casali, N Abecassis, S Bauer, R Biagini, S Bielack… - Annals of …, 2018 - Elsevier
Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

[HTML][HTML] Targeting molecular mechanisms underlying treatment efficacy and resistance in osteosarcoma: a review of current and future strategies

I Lilienthal, N Herold - International journal of molecular sciences, 2020 - mdpi.com
Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Targeting strategies for bone diseases: signaling pathways and clinical studies

H Xu, W Wang, X Liu, W Huang, C Zhu, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Since the proposal of Paul Ehrlich's magic bullet concept over 100 years ago, tremendous
advances have occurred in targeted therapy. From the initial selective antibody, antitoxin to …

Osteosarcoma

BR Eaton, R Schwarz, R Vatner, B Yeh… - Pediatric blood & …, 2021 - Wiley Online Library
Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This
paper reviews the general management and standard radiotherapy guidelines for …

Chondrosarcoma: a clinical review

A Gazendam, S Popovic, N Parasu… - Journal of Clinical …, 2023 - mdpi.com
Chondrosarcomas are a diverse group of malignant cartilaginous matrix-producing
neoplasms. Conventional chondrosarcomas are a continuum of disease based on the …

Ultra‐rare sarcomas: a consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities

S Stacchiotti, AM Frezza, JY Blay, EH Baldini… - Cancer, 2021 - Wiley Online Library
Background Among sarcomas, which are rare cancers, many types are exceedingly rare;
however, a definition of ultra‐rare cancers has not been established. The problem of ultra …

A novel signature to guide osteosarcoma prognosis and immune microenvironment: Cuproptosis-related lncRNA

M Yang, H Zheng, K Xu, Q Yuan, Y Aihaiti… - Frontiers in …, 2022 - frontiersin.org
Objective Osteosarcoma (OS) is a common bone malignancy with poor prognosis. We
aimed to investigate the relationship between cuproptosis-related lncRNAs (CRLncs) and …