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Chitosan‐based multifunctional nanomedicines and theranostics for targeted therapy of cancer
Nanotechnology as an emerging field has established inevitable impacts on nano‐
biomedicine and treatment of formidable diseases, inflammations, and malignancies. In this …
biomedicine and treatment of formidable diseases, inflammations, and malignancies. In this …
Chitosan biopolymer, its derivatives and potential applications in nano-therapeutics: A comprehensive review
Chitosan (CS) is a natural biopolymer used frequently in drug delivery because of its
biodegradability and biocompatibility. Several derivatives of CS have also been synthesized …
biodegradability and biocompatibility. Several derivatives of CS have also been synthesized …
Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer
Tumor hypoxia is a common feature of the tumor microenvironment and has been regarded
as one of the key factors in driving the emergence of drug resistance in solid tumors. To …
as one of the key factors in driving the emergence of drug resistance in solid tumors. To …
Chitosan modified by organo-functionalities as an efficient nanoplatform for anti-cancer drug delivery process
Cancer, one of the lethal threats to human health, is most frequently treated with surgery,
chemotherapy and radiation. Specific receptors and abnormal physiochemical conditions …
chemotherapy and radiation. Specific receptors and abnormal physiochemical conditions …
[HTML][HTML] Codelivery of genistein and miRNA-29b to A549 cells using aptamer-hybrid nanoparticle bioconjugates
K Sacko, K Thangavel, SA Shoyele - Nanomaterials, 2019 - mdpi.com
This study aimed to evaluate the anti-cancer effect of a combination therapy of miRNA-29b
and genistein loaded in mucin-1 (MUC 1)-aptamer functionalized hybrid nanoparticles in …
and genistein loaded in mucin-1 (MUC 1)-aptamer functionalized hybrid nanoparticles in …
Improved oral bioavailability and therapeutic efficacy of erlotinib through molecular complexation with phospholipid
The current study was aimed to prepare a molecular complex of erlotinib (ERL) with
phospholipid (PC) for enhancement of solubility and thus bioavailability, therapeutic efficacy …
phospholipid (PC) for enhancement of solubility and thus bioavailability, therapeutic efficacy …
Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation
Y Deng, W Luo, Z Zheng, G Wei, S Liu, Y Jiang… - Chemical Engineering …, 2023 - Elsevier
Co-amorphous (CA) formulation is a promising strategy to improve the solubility of poorly
water-soluble drugs, however, effective prediction of a CA system is a challenge. In this …
water-soluble drugs, however, effective prediction of a CA system is a challenge. In this …
Aptamer-conjugated chitosan-anchored liposomal complexes for targeted delivery of erlotinib to EGFR-mutated lung cancer cells
Lung cancer is the leading cancer and has the highest death rate. The epidermal growth
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
Study on the mechanism of surface modification of magnesium oxysulfate whisker
L Dang, X Nai, D Zhu, Y **g, X Liu, Y Dong, W Li - Applied surface science, 2014 - Elsevier
Hydrophobic-lipophilic magnesium oxysulfate whisker (MOSw) was prepared by surface
modification with lauric acid and the surface morphology of MOSw was examined with field …
modification with lauric acid and the surface morphology of MOSw was examined with field …
Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential …
M Perepelyuk, C Maher… - International Journal …, 2016 - Taylor & Francis
MicroRNAs (miRNAs) are potentially attractive candidates for cancer therapy. However, their
therapeutic application is limited by lack of availability of an efficient delivery system to stably …
therapeutic application is limited by lack of availability of an efficient delivery system to stably …