Introduction: The gastrointestinal mucosa constitutes a critical barrier where millions of
microbes and environmental antigens come in close contact with the host immune system …

Celiac disease (CD) is one of the most common diseases, resulting from both environmental
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …

Theterm gluten intolerance may refer to three types of human disorders: autoimmune celiac
disease (CD), allergy to wheat and non-celiac gluten sensitivity (NCGS). Gluten is a mixture …

Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in
genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was …

Celiac disease (CD) is a syndrome characterized by damage of the small intestinal mucosa
caused by the gliadin fraction of wheat gluten and similar alcohol-soluble proteins …

The macrophage is an essential part of the innate immune system and also serves as the
bridge between innate immunity and adaptive immune response. As the initiator and …

Celiac disease has become one of the best-understood HLA-linked disorders. Although it
shares many immunologic features with inflammatory bowel disease, celiac disease is …

Celiac Sprue | New England Journal of Medicine Skip to main content The New England Journal
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Objective. Little is known about the interaction of gliadin with intestinal epithelial cells and
the mechanism (s) through which gliadin crosses the intestinal epithelial barrier. We …

Background & Aims: Celiac disease is an immune-mediated enteropathy triggered by
gliadin, a component of the grain protein gluten. Gliadin induces an MyD88-dependent …