Antiviral activity of ribosome-inactivating proteins
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22)
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
Advances on delivery of cytotoxic enzymes as anticancer agents
Cancer is one of the most serious human diseases, causing millions of deaths worldwide
annually, and, therefore, it is one of the most investigated research disciplines. Develo** …
annually, and, therefore, it is one of the most investigated research disciplines. Develo** …
Advances on tumor-targeting delivery of cytotoxic proteins
Great attention has been paid to cytotoxic proteins (eg, ribosome-inactivating proteins, RIPs)
possessing high anticancer activities; unlike small drugs, cytotoxic proteins can effectively …
possessing high anticancer activities; unlike small drugs, cytotoxic proteins can effectively …
Structural and functional investigation and pharmacological mechanism of trichosanthin, a type 1 ribosome-inactivating protein
Trichosanthin (TCS) is an RNA N-glycosidase that depurinates adenine-4324 in the
conserved α-sarcin/ricin loop (α-SRL) of rat 28 S ribosomal RNA (rRNA). TCS has only one …
conserved α-sarcin/ricin loop (α-SRL) of rat 28 S ribosomal RNA (rRNA). TCS has only one …
[HTML][HTML] Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma
Z Deng, YJ Teng, Q Zhou, ZG Ouyang… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Hepatocellular carcinoma (HCC) is characterized by dysregulation of the
immune microenvironment and the development of chemoresistance. Specifically …
immune microenvironment and the development of chemoresistance. Specifically …
[PDF][PDF] Antiviral Activity of Ribosome-Inactivating Proteins. Toxins 2021, 13, 80
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22)
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3
JL Li, H Li, ZL Zhang, NY Wang, YC Zhang - Biological Research, 2016 - Springer
Context Trichosanthin produced in the root tube of Trichosanthes kirilowii shows anti-tumor
activity on a series of cancer cells including Hela, MCF-7, HL-60. But there is little …
activity on a series of cancer cells including Hela, MCF-7, HL-60. But there is little …
Role of STAT1 in the resistance of HBV to IFN‑α
B Xu, B Tang, J Wei - Experimental and Therapeutic …, 2021 - spandidos-publications.com
The objective of the present study was to explore the mechanism of hepatitis B virus (HBV)
resistance to interferon (IFN), and the role of signal transducer and activator of transcription …
resistance to interferon (IFN), and the role of signal transducer and activator of transcription …
The ethyl acetate extracts of radix trichosanthis protect retinal vascular endothelial cells from high glucose-induced injury
Y Song, Z Wang, H Li, W **ng, Y Wu, C Li, Y Liu… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance. Radix trichosanthis (RT) is a popular plant in China to
treat diabetes. Aim of the study The aim of this study is to investigate the therapeutic effect of …
treat diabetes. Aim of the study The aim of this study is to investigate the therapeutic effect of …
Network Pharmacology Analysis of the Therapeutic Mechanisms Underlying Beimu‐Gualou Formula Activity against Bronchiectasis with In Silico Molecular Docking …
X Shen, H Li, WJ Zou, JM Wu, L Wang… - Evidence‐Based …, 2021 - Wiley Online Library
Background. The classical Chinese herbal prescription Beimu‐Gualou formula (BMGLF) has
been diffusely applied to the treatment of respiratory diseases, including bronchiectasis …
been diffusely applied to the treatment of respiratory diseases, including bronchiectasis …