Multimodal machine learning in precision health: A sco** review

A Kline, H Wang, Y Li, S Dennis, M Hutch, Z Xu… - npj Digital …, 2022 - nature.com
Abstract Machine learning is frequently being leveraged to tackle problems in the health
sector including utilization for clinical decision-support. Its use has historically been focused …

Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Prevention of psychosis: advances in detection, prognosis, and intervention

P Fusar-Poli, GS De Pablo, CU Correll… - JAMA …, 2020 - jamanetwork.com
Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …

Brain disorders? Not really: Why network structures block reductionism in psychopathology research

D Borsboom, AOJ Cramer, A Kalis - Behavioral and Brain Sciences, 2019 - cambridge.org
In the past decades, reductionism has dominated both research directions and funding
policies in clinical psychology and psychiatry. The intense search for the biological basis of …

Improving mental health services: A 50-year journey from randomized experiments to artificial intelligence and precision mental health

L Bickman - Administration and Policy in Mental Health and Mental …, 2020 - Springer
This conceptual paper describes the current state of mental health services, identifies critical
problems, and suggests how to solve them. I focus on the potential contributions of artificial …

Association of structural magnetic resonance imaging measures with psychosis onset in individuals at clinical high risk for develo** psychosis: an ENIGMA working …

M Jalbrzikowski, RA Hayes, SJ Wood… - JAMA …, 2021 - jamanetwork.com
Importance The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled
neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological …

Accelerated cortical thinning precedes and predicts conversion to psychosis: The NAPLS3 longitudinal study of youth at clinical high-risk

MA Collins, JL Ji, Y Chung, CA Lympus… - Molecular …, 2023 - nature.com
Progressive grey matter loss has been demonstrated among clinical high-risk (CHR)
individuals who convert to psychosis, but it is unknown whether these changes occur prior to …

Implementing precision psychiatry: a systematic review of individualized prediction models for clinical practice

G Salazar de Pablo, E Studerus… - Schizophrenia …, 2021 - academic.oup.com
Background The impact of precision psychiatry for clinical practice has not been
systematically appraised. This study aims to provide a comprehensive review of validated …

What causes the onset of psychosis in individuals at clinical high risk? A meta-analysis of risk and protective factors

D Oliver, TJ Reilly, O Baccaredda Boy… - Schizophrenia …, 2020 - academic.oup.com
Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

Early detection and preventive intervention in schizophrenia: from fantasy to reality

JA Lieberman, SA Small… - American Journal of …, 2019 - Am Psychiatric Assoc
Scientific progress in understanding human disease can be measured by the effectiveness
of its treatment. Antipsychotic drugs have been proven to alleviate acute psychotic symptoms …