[HTML][HTML] CLIP and complementary methods

M Hafner, M Katsantoni, T Köster, J Marks… - Nature Reviews …, 2021 - nature.com
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

Detecting RNA modifications in the epitranscriptome: predict and validate

M Helm, Y Motorin - Nature Reviews Genetics, 2017 - nature.com
RNA modifications are emerging players in the field of post-transcriptional regulation of
gene expression, and are attracting a comparable degree of research interest to DNA and …

An overview of microRNAs

SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids

OD Murillo, W Thistlethwaite, J Rozowsky… - Cell, 2019 - cell.com
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …

Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics

B Dhondt, C Pinheiro, E Geeurickx… - Journal of …, 2023 - Wiley Online Library
The analysis of extracellular vesicles (EV) in blood samples is under intense investigation
and holds the potential to deliver clinically meaningful biomarkers for health and disease …

Clinical relevance of circulating cell-free microRNAs in cancer

H Schwarzenbach, N Nishida, GA Calin… - Nature reviews Clinical …, 2014 - nature.com
Efficient patient management relies on early diagnosis of disease and monitoring of
treatment. In this regard, much effort has been made to find informative, blood-based …

[HTML][HTML] Next generation sequencing technology: advances and applications

HPJ Buermans, JT Den Dunnen - … Acta (BBA)-Molecular Basis of Disease, 2014 - Elsevier
Impressive progress has been made in the field of Next Generation Sequencing (NGS).
Through advancements in the fields of molecular biology and technical engineering …

Library construction for next-generation sequencing: overviews and challenges

SR Head, HK Komori, SA LaMere, T Whisenant… - …, 2014 - Taylor & Francis
High-throughput sequencing, also known as next-generation sequencing (NGS), has
revolutionized genomic research. In recent years, NGS technology has steadily improved …

MicroRNA profiling: approaches and considerations

CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

NT Ingolia, GA Brar, S Rouskin, AM McGeachy… - Nature protocols, 2012 - nature.com
Recent studies highlight the importance of translational control in determining protein
abundance, underscoring the value of measuring gene expression at the level of translation …