Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease affecting
motor neurons with an incidence of about 1/100,000. Most ALS cases are sporadic, but 5 …

Objective: To systematically review evidence bearing on the management of patients with
amyotrophic lateral sclerosis (ALS). Methods: The authors analyzed studies from 1998 to …

A growing body of evidence suggests that inflammation, mitochondrial dysfunction and
oxidant-antioxidant imbalance may play a significant role in the development and …

Chronic pain is a frequent component of many neurological disorders, affecting 20–40% of
patients for many primary neurological diseases. These diseases result from a wide range of …

The main aims in the care of individuals with amyotrophic lateral sclerosis (ALS) are to
minimize morbidity and maximize quality of life. Although no cure exists for ALS, supportive …

The current study investigated the effects of psychological well-being measured as quality of
life (QoL), depression, current mood and motivation on brain–computer interface (BCI) …

It is now well recognized that, in addition to motor impairment, amyotrophic lateral sclerosis
(ALS) may cause extra-motor clinical signs and symptoms. These can include the alteration …

Amyotrophic lateral sclerosis (ALS) is a debilitating motor neurological disorder for which
there is still no cure. The disease seriously jeopardizes the health and lifespan of adult …

The locked-in syndrome (LIS) describes patients who are awake and conscious but severely
deefferented leaving the patient in a state of almost complete immobility and loss of verbal …

The pathogenesis of several neuropsychiatric disorders, including anxiety and depression,
has been linked to oxidative stress, in part via alterations in cyclic nucleotide signaling …