Abstract Purpose of Review Patients with inflammatory arthropathies have a high rate of
fragility fractures. Diagnostic assessment and monitoring of bone density and quality are …

Micro computed tomography (µCT) follows the same principle of computed-tomography
used for patients, however providing higher-resolution. Using a non-destructive approach …

Transcortical vessels (TCVs) provide effective communication between bone marrow
vascular system and external circulation. Although osteocytes are in close contact with them …

Context Reduced bone material strength index (BMSi) and increased cortical porosity (CtPo)
have emerged as potentially contributing to fracture risk in type 2 diabetes mellitus (T2DM) …

Biodegradable magnesium (Mg) alloys can revolutionize osteosynthesis, because they have
mechanical properties similar to those of the bone, and degrade over time, avoiding the …

Bone is organized in a hierarchical 3D architecture. Traditionally, analysis of the skeletal
system was based on bone mass assessment by radiographic methods or on the …

Roux‐en‐Y gastric bypass (RYGB) surgery is a highly effective treatment for obesity but
negatively affects the skeleton. Studies of skeletal effects have generally examined areal …

Numerous clinical cohorts are exposed to reduced skeletal loading and associated bone
loss, including surgical patients, stroke and spinal cord injury victims, and women on bed …

Bone strength is dependent on bone density and microstructure. High-resolution peripheral
quantitative computed tomography (HR-pQCT) can measure microstructure but is somewhat …

Cortical bone loss is not fully assessed by the current X-ray methods, and there is an unmet
need in identifying women at risk of osteoporotic fracture, who should receive a treatment …