Vascular adaptation to exercise in humans: role of hemodynamic stimuli
On the 400th anniversary of Harvey's Lumleian lectures, this review focuses on
“hemodynamic” forces associated with the movement of blood through arteries in humans …
“hemodynamic” forces associated with the movement of blood through arteries in humans …
Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives
JJ Chiu, S Chien - Physiological reviews, 2011 - journals.physiology.org
Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …
functions and vascular biology/pathobiology in health and disease. The flow patterns and …
Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
PF Davies - Nature clinical practice Cardiovascular medicine, 2009 - nature.com
Endothelium lining the cardiovascular system is highly sensitive to hemodynamic shear
stresses that act at the vessel luminal surface in the direction of blood flow. Physiological …
stresses that act at the vessel luminal surface in the direction of blood flow. Physiological …
MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation
J Zhou, KC Wang, W Wu… - Proceedings of the …, 2011 - National Acad Sciences
Adhesion of circulating monocytes to vascular endothelial cells (ECs) is a critical event
leading to vascular inflammation and, hence, development of atherosclerosis. MicroRNAs …
leading to vascular inflammation and, hence, development of atherosclerosis. MicroRNAs …
Perspective on CFD studies of coronary artery disease lesions and hemodynamics: a review
Coronary artery disease (CAD) is the most common cardiovascular disease. Early diagnosis
of CAD's physiological significance is of utmost importance for guiding individualized risk …
of CAD's physiological significance is of utmost importance for guiding individualized risk …
Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress
S Pan - Antioxidants & redox signaling, 2009 - liebertpub.com
The endothelium lining the inner surface of blood vessels of the cardiovascular system is
constantly exposed to hemodynamic shear stress. The interaction between endothelial cells …
constantly exposed to hemodynamic shear stress. The interaction between endothelial cells …
Endothelial cell polarization and orientation to flow in a novel microfluidic multimodal shear stress generator
Endothelial cells (EC) respond to shear stress to maintain vascular homeostasis, and a
disrupted response is associated with cardiovascular diseases. To understand how different …
disrupted response is associated with cardiovascular diseases. To understand how different …
A validated predictive model of coronary fractional flow reserve
Y Huo, M Svendsen, JS Choy… - Journal of The …, 2012 - royalsocietypublishing.org
Myocardial fractional flow reserve (FFR), an important index of coronary stenosis, is
measured by a pressure sensor guidewire. The determination of FFR, only based on the …
measured by a pressure sensor guidewire. The determination of FFR, only based on the …
Patient-specific three-dimensional simulation of LDL accumulation in a human left coronary artery in its healthy and atherosclerotic states
We calculate low-density lipoprotein (LDL) transport from blood into arterial walls in a three-
dimensional, patient-specific model of a human left coronary artery. The in vivo anatomy …
dimensional, patient-specific model of a human left coronary artery. The in vivo anatomy …
Uncertainty quantification of a three-dimensional in-stent restenosis model with surrogate modelling
In-stent restenosis is a recurrence of coronary artery narrowing due to vascular injury
caused by balloon dilation and stent placement. It may lead to the relapse of angina …
caused by balloon dilation and stent placement. It may lead to the relapse of angina …