Molecular ultrasound imaging: current status and future directions

N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …

Advances in molecular imaging with ultrasound

R Gessner, PA Dayton - Molecular imaging, 2010 - journals.sagepub.com
Ultrasound imaging has long demonstrated utility in the study and measurement of anatomic
features and noninvasive observation of blood flow. Within the last decade, advances in …

An in vivo validation of the application of acoustic radiation force to enhance the diagnostic utility of molecular imaging using 3-D ultrasound

RC Gessner, JE Streeter, R Kothadia… - Ultrasound in medicine …, 2012 - Elsevier
For more than a decade, the application of acoustic radiation force (ARF) has been
proposed as a mechanism to increase ultrasonic molecular imaging (MI) sensitivity in vivo …

Real-time technique for improving molecular imaging and guiding drug delivery in large blood vessels: in vitro and ex vivo results

AV Patil, JJ Rychak, AL Klibanov… - Molecular …, 2011 - journals.sagepub.com
Ultrasound-based molecular imaging employs targeted microbubbles to image vascular
pathology. This approach also has the potential to monitor molecularly targeted microbubble …

Validation of normalized singular spectrum area as a classifier for molecularly targeted microbubble adherence

EB Herbst, S Unnikrishnan, AL Klibanov… - Ultrasound in medicine …, 2019 - Elsevier
Ultrasound molecular imaging is a diagnostic technique wherein molecularly targeted
microbubble contrast agents are imaged to reveal disease markers on the blood vessel …

Real-time targeted molecular imaging using singular value spectra properties to isolate the adherent microbubble signal

FW Mauldin, AH Dhanaliwala, AV Patil… - Physics in Medicine & …, 2012 - iopscience.iop.org
Ultrasound-based real-time molecular imaging in large blood vessels holds promise for
early detection and diagnosis of various important and significant diseases, such as stroke …

Acoustic radiation force for vascular cell therapy: in vitro validation

M Kaya, C Toma, J Wang, M Grata, H Fu… - Ultrasound in medicine …, 2012 - Elsevier
Cell-based therapeutic approaches are attractive for the restoration of the protective
endothelial layer in arteries affected by atherosclerosis or following angioplasty and …

Hybrid dual frequency transducer and scanhead for micro-ultrasound imaging

M Lukacs, M Lee, E Cherin, J Yin… - 2009 IEEE …, 2009 - ieeexplore.ieee.org
We report on the design, assembly and evaluation of a dual frequency mechanically
scanned transducer for ultrasound bubble manipulation and real time high frequency …

Counter flow microbubble channeling using acoustic radiation force funnel

B Raiton, JR McLaughlan, PR Smith… - 2011 IEEE …, 2011 - ieeexplore.ieee.org
Acoustic radiation force has become a significant factor in the research to enhance the
targeting of microbubbles for molecular imaging and drug delivery. In this study …

3D radiation force enhanced ultrasonic molecular imaging with a clinical system

JE Streeter, RC Gessner… - 2011 IEEE International …, 2011 - ieeexplore.ieee.org
For over a decade, acoustic radiation force (ARF) has been proposed as a method to
enhance microbubble contrast agent (MCA) retention in ultrasonic molecular imaging …