A review on development of bio-active thiosemicarbazide derivatives: Recent advances
There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …
with diverse biological activities in recent years. Therefore, many scientists have prepared …
Recent update on antibacterial and antifungal activity of quinoline scaffolds
A Dorababu - Archiv der Pharmazie, 2021 - Wiley Online Library
Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
A quinquennial review on recent advancements and developments in search of anti-malarial agents
TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …
estimated to kill between one and two million people (mainly children) every year. Novel anti …
Current pharmaceutical aspects of synthetic quinoline derivatives
Quinoline derivatives are considered broad-spectrum pharmacological compounds that
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …
Quinoline: an attractive scaffold in drug design
LFE Moor, TRA Vasconcelos… - Mini Reviews in …, 2021 - benthamdirect.com
Quinoline and its derivatives comprise an important group of heterocyclic compounds that
exhibits a wide range of pharmacological properties such as antibacterial, antiviral …
exhibits a wide range of pharmacological properties such as antibacterial, antiviral …
Medicinal chemistry updates on quinoline-and endoperoxide-based hybrids with potent antimalarial activity
The resistance of conventional antimalarial drugs against the malarial parasite continues to
pose a challenge to control the disease. The indiscriminate exploitation of the available …
pose a challenge to control the disease. The indiscriminate exploitation of the available …
Quinoline: a promising scaffold in recent antiprotozoal drug discovery
A Dorababu - ChemistrySelect, 2021 - Wiley Online Library
Protozoal infections malaria and leishmania have become most prevalent in recent times. A
high death rate is reported world‐wide because of these diseases. Although there are only a …
high death rate is reported world‐wide because of these diseases. Although there are only a …
Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases
H Shamshad, R Bakri, AZ Mirza - Molecular Biology Reports, 2022 - Springer
Parasitic diseases have a serious impact on the world in terms of health and economics and
are responsible for worldwide mortality and morbidity. The present review features the …
are responsible for worldwide mortality and morbidity. The present review features the …
Recent contributions of quinolines to antimalarial and anticancer drug discovery research
T Van de Walle, L Cools, S Mangelinckx… - European Journal of …, 2021 - Elsevier
Quinoline, a privileged scaffold in medicinal chemistry, has always been associated with a
multitude of biological activities. Especially in antimalarial and anticancer research …
multitude of biological activities. Especially in antimalarial and anticancer research …
Microwave assisted synthesis, biological activities, and in silico investigation of some benzimidazole derivatives
Some derivatives of 2‐substituted benzimidazole were prepared via coupling of N‐methyl‐o‐
phenylenediamine or o‐phenylenediamine with different aromatic aldehydes catalyzed by …
phenylenediamine or o‐phenylenediamine with different aromatic aldehydes catalyzed by …