A review on development of bio-active thiosemicarbazide derivatives: Recent advances

PT Acharya, ZA Bhavsar, DJ Jethava, DB Patel… - Journal of Molecular …, 2021 - Elsevier
There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …

Recent update on antibacterial and antifungal activity of quinoline scaffolds

A Dorababu - Archiv der Pharmazie, 2021 - Wiley Online Library
Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …

A quinquennial review on recent advancements and developments in search of anti-malarial agents

TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

Current pharmaceutical aspects of synthetic quinoline derivatives

R Tabassum, M Ashfaq, H Oku - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Quinoline derivatives are considered broad-spectrum pharmacological compounds that
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …

Quinoline: an attractive scaffold in drug design

LFE Moor, TRA Vasconcelos… - Mini Reviews in …, 2021 - benthamdirect.com
Quinoline and its derivatives comprise an important group of heterocyclic compounds that
exhibits a wide range of pharmacological properties such as antibacterial, antiviral …

Medicinal chemistry updates on quinoline-and endoperoxide-based hybrids with potent antimalarial activity

A Uddin, M Chawla, I Irfan, S Mahajan… - RSC Medicinal …, 2021 - pubs.rsc.org
The resistance of conventional antimalarial drugs against the malarial parasite continues to
pose a challenge to control the disease. The indiscriminate exploitation of the available …

Quinoline: a promising scaffold in recent antiprotozoal drug discovery

A Dorababu - ChemistrySelect, 2021 - Wiley Online Library
Protozoal infections malaria and leishmania have become most prevalent in recent times. A
high death rate is reported world‐wide because of these diseases. Although there are only a …

Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases

H Shamshad, R Bakri, AZ Mirza - Molecular Biology Reports, 2022 - Springer
Parasitic diseases have a serious impact on the world in terms of health and economics and
are responsible for worldwide mortality and morbidity. The present review features the …

Recent contributions of quinolines to antimalarial and anticancer drug discovery research

T Van de Walle, L Cools, S Mangelinckx… - European Journal of …, 2021 - Elsevier
Quinoline, a privileged scaffold in medicinal chemistry, has always been associated with a
multitude of biological activities. Especially in antimalarial and anticancer research …

Microwave assisted synthesis, biological activities, and in silico investigation of some benzimidazole derivatives

ZA Bhavsar, PT Acharya, DJ Jethava… - Journal of …, 2020 - Wiley Online Library
Some derivatives of 2‐substituted benzimidazole were prepared via coupling of N‐methyl‐o‐
phenylenediamine or o‐phenylenediamine with different aromatic aldehydes catalyzed by …