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TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target
RY Li, Q Qin, HC Yang, YY Wang, YX Mi, YS Yin… - Molecular …, 2022 - Springer
Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane
immune receptor that is mainly expressed on microglia in the brain and macrophages in the …
immune receptor that is mainly expressed on microglia in the brain and macrophages in the …
Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis
Background Existing meta-analyses on omega-3 polyunsaturated fatty acids and their anti-
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …
[HTML][HTML] Revolutionary auxetic intravascular medical stents for angioplasty applications
Due to the significant mortality rate associated with atherosclerosis-induced cardiovascular
disease, the utilization of advanced intravascular stents with superior mechanical …
disease, the utilization of advanced intravascular stents with superior mechanical …
Endoplasmic reticulum stress activates unfolded protein response signaling and mediates inflammation, obesity, and cardiac dysfunction: therapeutic and molecular …
Obesity has been implicated as a risk factor for insulin resistance and cardiovascular
diseases (CVDs). Although the association between obesity and CVD is a well-established …
diseases (CVDs). Although the association between obesity and CVD is a well-established …
[HTML][HTML] TREM2 regulates microglial lipid droplet formation and represses post-ischemic brain injury
Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor
protein predominantly expressed in microglia within the central nervous system (CNS) …
protein predominantly expressed in microglia within the central nervous system (CNS) …
Materials for immunotherapy
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …
preclinical studies. The interplay of chemistry and materials has resulted in improved …
The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc
The contribution of mitochondria to the metabolic function of hypoxic NP cells has been
overlooked. We have shown that NP cells contain networked mitochondria and that …
overlooked. We have shown that NP cells contain networked mitochondria and that …
Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?
Lipids are essential for physiological processes such as maintaining membrane integrity,
providing a source of energy and acting as signalling molecules to control processes …
providing a source of energy and acting as signalling molecules to control processes …
The association between metabolic syndrome components and the development of atherosclerosis
Metabolic syndrome (MetS) is a collection of pathological conditions associated with
metabolic, pro-inflammatory, and prothrombotic states. MetS plays an essential role in the …
metabolic, pro-inflammatory, and prothrombotic states. MetS plays an essential role in the …
Adaptive (T and B cells) immunity and control by dendritic cells in atherosclerosis
H Ait-Oufella, AP Sage, Z Mallat, A Tedgui - Circulation research, 2014 - ahajournals.org
Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …