Approaches for bacteriophage genome engineering
In recent years, bacteriophage research has been boosted by a rising interest in using
phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to …
phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to …
Engineered bacteriophage therapeutics: rationale, challenges and future
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing
CRISPR-Cas13 proteins are RNA-guided RNA nucleases that defend against incoming
RNA and DNA phages by binding to complementary target phage transcripts followed by …
RNA and DNA phages by binding to complementary target phage transcripts followed by …
Genetic engineering of bacteriophages against infectious diseases
Bacteriophages (phages) are the most abundant and widely distributed organisms on Earth,
constituting a virtually unlimited resource to explore the development of biomedical …
constituting a virtually unlimited resource to explore the development of biomedical …
The many applications of engineered bacteriophages—An overview
Since their independent discovery by Frederick Twort in 1915 and Felix d'Herelle in 1917,
bacteriophages have captured the attention of scientists for more than a century. They are …
bacteriophages have captured the attention of scientists for more than a century. They are …
Engineering bacteriophages as versatile biologics
Viruses of bacteria (bacteriophages or phages) are highly evolved nanomachines that
recognize bacterial cell walls, deliver genetic information, and kill or transform their targets …
recognize bacterial cell walls, deliver genetic information, and kill or transform their targets …
Application of bacteriophages in the agro-food sector: A long way toward approval
L Fernández, D Gutiérrez, A Rodríguez… - Frontiers in cellular and …, 2018 - frontiersin.org
The rapid increase in multi-drug resistant (MDR) pathogens has put notable pressure on
Health Authorities, who foresee an uncertain future for global human health. In June 2017 …
Health Authorities, who foresee an uncertain future for global human health. In June 2017 …
Progress and prospect: Biosynthesis of plant natural products based on plant chassis
J Lin, X Yin, Y Zeng, X Hong, S Zhang, B Cui… - Biotechnology …, 2023 - Elsevier
Plant-derived natural products are a specific class of active substances with numerous
applications in the medical, energy, and industrial fields. Many of these substances are in …
applications in the medical, energy, and industrial fields. Many of these substances are in …
Bacteriophage and endolysin engineering for biocontrol of food pathogens/pathogens in the food: recent advances and future trends
C Lee, H Kim, S Ryu - CritiCal reviews in Food sCienCe and …, 2023 - Taylor & Francis
Despite advances in modern technologies, various foodborne outbreaks have continuously
threatened the food safety. The overuse of and abuse/misuse of antibiotics have escalated …
threatened the food safety. The overuse of and abuse/misuse of antibiotics have escalated …
Engineering Phages to Fight Multidrug-Resistant Bacteria
Facing the global “superbug” crisis due to the emergence and selection for antibiotic
resistance, phages are among the most promising solutions. Fighting multidrug-resistant …
resistance, phages are among the most promising solutions. Fighting multidrug-resistant …