COVID-19 is an evolving systemic inflammatory pandemic disease, predominantly affecting
the respiratory system. Associated cardiovascular comorbid conditions result in severe to …

Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical
manifestations that makes it difficult to detect and treat. It is also one of the major and most …

Sepsis is a complex of life-threating organ dysfunction in critically ill patients, with a primary
infectious cause or through secondary infection of damaged tissues. The systemic …

Sepsis is a multifactorial syndrome primarily determined by the host response to an invading
pathogen. It is common, with over 48 million cases worldwide in 2017, and often lethal. The …

Capillary leak syndrome (CLS) represents a phenotype of increased fluid extravasation,
resulting in intravascular hypovolemia, extravascular edema formation and ultimately …

As the prevalence of heart failure (HF) continues to rise, prompt diagnosis and management
of various medical conditions, which may lead to HF exacerbation and result in poor patient …

Critical care medicine is a medical specialty engaging the diagnosis and treatment of
critically ill patients who have or are likely to have life-threatening organ failure. Sepsis, a life …

Background Mottling score, a tissue perfusion parameter, is correlated with outcome in
septic shock patients. However, its predictive value on mortality according to prognostic …

The burden of pandemic COVID-19 is growing worldwide, as the continuous increases of
contagion. Only 10–15% of the entire infected population has the necessity of intensive care …

Sepsis and septic shock are the leading cause of admission and mortality in non-coronary
intensive care units. Currently, however, no specific treatments are available for this …