Background The World Health Organization recommends uncomplicated P. falciparum
malaria is treated using Artemisinin‐based Combination Therapy (ACT). This review aims to …

Sulfadoxine–pyrimethamine (SP) is used throughout Africa for intermittent preventive
treatment (IPT) of malaria, but resistance threatens its efficacy. We found marked regional …

Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the
artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum …

Background Although the molecular basis of resistance to a number of common antimalarial
drugs is well known, a geographic description of the emergence and dispersal of resistance …

Background An assessment of the accuracy of Paracheck Pf®, a malaria rapid diagnostic
test (RDT) detecting histidine rich protein 2 was undertaken amongst children aged 6–59 …

Background Individual patient data (IPD) meta‐analysis is the gold standard. Aggregate
data (AD) and IPD can be combined using conventional pairwise meta‐analysis when IPD …

Apicomplexan parasites include many parasites of importance either for livestock or as
causative agents of human diseases. The importance of these parasites has been …

Background Artesunate and amodiaquine (AS&AQ) is at present the world's second most
widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the …

Background. The development of novel artemisinin-combination therapies suitable for the
treatment of pediatric patients suffering from malaria is a research priority. The aim of this …

Abstract Background Increasing resistance of Plasmodium falciparum to sulfadoxine-
pyrimethamine (SP) threatens its usefulness for intermittent preventive treatment in …