Two-photon voltage imaging has long been heralded as a transformative approach capable
of answering many long-standing questions in modern neuroscience. However, exploiting …

Astrocytes are a direct target of neuromodulators and can influence neuronal activity on
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …

The use of wavefront sha** has found extensive application to develop ultra-thin
endoscopic techniques based on multimode optical fibers (MMF), leveraging on the ability to …

Coherent fiber bundles are widely used for endoscopy, but conventional approaches require
distal optics to form an object image and acquire pixelated information owing to the …

As miniaturization becomes a growing trend in optical systems, the ability to precisely
manipulate wavefronts within micrometric pupils becomes crucial. Extensive efforts to …

Optogenetics promises to manipulate the brain circuitry by exciting or inhibiting the same
neurons via different colors of light (ie, bidirectionality), and furthermore, to co-work with …

The prefrontal cortex (PFC) is a hub for cognitive behaviors and is a key target for
neuroadaptations in alcohol use disorders. Recent advances in genetically encoded …

Cell therapy has proven to be a promising treatment for a range of neurological disorders,
including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after …

The development of efficient genetically encoded indicators and actuators has opened up
the possibility of reading and manipulating neuronal activity in living tissues with light. To …

Miniature two-photon microscopy has emerged as a powerful technique for investigating
brain activity in freely moving animals. Ongoing research objectives include reducing probe …