[HTML][HTML] Nanotheranostics-based management of head and neck cancer
Head and neck cancer is affecting a large sort of population. Many treatments are available
on a regular base, but they have their limitations. Diagnosis in the early stage is essential to …
on a regular base, but they have their limitations. Diagnosis in the early stage is essential to …
Shedding Light on Chemoresistance: The Perspective of Photodynamic Therapy in Cancer Management
The persistent failure of standard chemotherapy underscores the urgent need for innovative
and targeted approaches in cancer treatment. Photodynamic therapy (PDT) has emerged as …
and targeted approaches in cancer treatment. Photodynamic therapy (PDT) has emerged as …
A Physiochemical, In Vitro, and In Vivo Comparative Analysis of Verteporfin–Lipid Conjugate Formulations: Solid Lipid Nanoparticles and Liposomes
VisudyneⓇ, a liposomal formulation of verteporfin (benzoporphyrin derivative; BPD), is the
only nanomedicine approved to date for photodynamic therapy (PDT). We have previously …
only nanomedicine approved to date for photodynamic therapy (PDT). We have previously …
PD‐L1 Immune Checkpoint Targeted Photoactivable Liposomes (iTPALs) Prime the Stroma of Pancreatic Tumors and Promote Self‐Delivery
Desmoplasia in pancreatic ductal adenocarcinoma (PDAC) limits the penetration and
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
A single photodynamic priming protocol augments delivery of⍺‐PD‐L 1 m A bs and induces immunogenic cell death in head and neck tumors
C Bhandari, A Moffat, J Fakhry… - Photochemistry and …, 2024 - Wiley Online Library
Photodynamic priming (PDP) leverages the photobiological effects of subtherapeutic
photodynamic therapy (PDT) regimens to modulate the tumor vasculature and stroma. PDP …
photodynamic therapy (PDT) regimens to modulate the tumor vasculature and stroma. PDP …
Enabling in vivo optical imaging of an osmium photosensitizer by micellar formulation
Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption,
favoring PDT activity at greater tissue depths. We recently reported on a potent Os (II) PS …
favoring PDT activity at greater tissue depths. We recently reported on a potent Os (II) PS …
Increasing the Dye Payload of Cetuximab-IRDye800CW Enables Photodynamic Therapy
Cetuximab (Cet)-IRDye800CW, among other antibody-IRDye800CW conjugates, is a
potentially effective tool for delineating tumor margins during fluorescence image-guided …
potentially effective tool for delineating tumor margins during fluorescence image-guided …
Advanced Nanomedicine for High-Risk HPV-Driven Head and Neck Cancer
Q Xu, Y Chen, Y **, Z Wang, H Dong, AM Kaufmann… - Viruses, 2022 - mdpi.com
The incidence of high-risk Human Papillomavirus (HR-HPV)-driven head and neck
squamous cell carcinoma (HNSCC) is on the rise globally. HR-HPV-driven HNSCC displays …
squamous cell carcinoma (HNSCC) is on the rise globally. HR-HPV-driven HNSCC displays …
[HTML][HTML] Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma
Y Zhang, Z Li, C Zhang, C Shao, Y Duan, G Zheng… - Neoplasia, 2025 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) are the most common type of head and
neck tumor that severely threatens human health due to its highly aggressive nature and …
neck tumor that severely threatens human health due to its highly aggressive nature and …
Temporal dynamics of fluorescence and photoacoustic signals of a Cetuximab-IRDye800 conjugate in EGFR-overexpressing tumors
Molecular fluorescence-guided surgery has shown promise for tumor margin delineation but
is limited by its depth profiling capability. Interestingly, most fluorophores, either clinically …
is limited by its depth profiling capability. Interestingly, most fluorophores, either clinically …