Reactive oxygen species (ROS) are an unenviable part of aerobic life. Their steady-state
concentration is a balance between production and elimination providing certain steady …

Changes in the intracellular thiol–disulfide balance are considered major determinants in
the redox status/signaling of the cell. Cellular signaling is very sensitive to both exogenous …

Protein oxidative modifications, also known as protein oxidation, are a major class of protein
posttranslational modifications. They are caused by reactions between protein amino acid …

I. Introduction II. Classification of Plant Prxs and Their Distribution in Plants and
Cyanobacteria III. Peroxidase Activity of Peroxiredoxins IV. Conformational Dynamics and …

Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …

Protein S-glutathionylation, the reversible formation of mixed disulfides between glutathione
and low-pKa cysteinyl residues, not only is a cellular response to mild oxidative/nitrosative …

Skeletal muscle fibers continually generate reactive oxygen species (ROS) at a slow rate
that increases during muscle contraction. This activity-dependent increase in ROS …

Glutathione (GSH) is the most abundant antioxidant and a major detoxification agent in cells.
It is synthesized through two-enzyme reaction catalyzed by glutamate cysteine ligase and …

Reactive oxygen species (ROS) are by-products of the cellular metabolism of oxygen
consumption, produced mainly in the mitochondria. ROS are known to be highly reactive …

The turn of the century welcomed major developments in redox biology. In plants,
proteomics made possible the identification of proteins linked to thioredoxin (Trx), initially in …