Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

Background Despite increasing clinical investigations emphasizing the safety of
mesenchymal stem cell (MSC) therapy in different populations with different diseases, no …

Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Aging is an inevitable biological process and is accompanied by a gradual decline of
physiological functions, such as the incidence of age-related diseases. Aging becomes a …

Immune system is a versatile and dynamic body organ which offers survival and endurance
of human beings in their hostile living environment. However, similar to other cells, immune …

Stem cells in the adult pituitary are quiescent yet show acute activation upon tissue injury.
The molecular mechanisms underlying this reaction are completely unknown. We applied …

Aging is associated with a low-grade, systemic inflammatory state defined as
“inflammaging”, ruled by the loss of proper regulation of the immune system leading to the …

Aging is a complex biological process with multifactorial nature underlined by genetic,
environmental, and social factors. In the present paper, we review several mechanisms of …

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a novel evolutionarily
conserved protein present in both vertebrate and invertebrate species. MANF shows distinct …