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Recent advances in the chemistry and biology of benzothiazoles
Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five‐
membered thiazole ring. This moiety has attracted considerable attention because of its …
membered thiazole ring. This moiety has attracted considerable attention because of its …
Biological aspects of emerging benzothiazoles: a short review
In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …
attention due to their useful biological and pharmacological properties. Benzothiazole is …
Curcumin-I Knoevenagel's condensates and their Schiff's bases as anticancer agents: synthesis, pharmacological and simulation studies
Pyrazolealdehydes (4a–d), Knoevenagel's condensates (5a–d) and Schiff's bases (6a–d) of
curcumin-I were synthesized, purified and characterized. Hemolysis assays, cell line …
curcumin-I were synthesized, purified and characterized. Hemolysis assays, cell line …
Curcumin based pyrazole-thiazole hybrids as antiproliferative agents: Synthesis, pharmacokinetic, photophysical properties, and docking studies
A series of new curcumin pyrazole-thiazole hybrids (C 1-C 8) were synthesized and
characterized by fundamental spectral analysis. The synthesized compounds were tested for …
characterized by fundamental spectral analysis. The synthesized compounds were tested for …
The potency of heterocyclic curcumin analogues: An evidence-based review
Curcumin, a potent phytochemical, has been a significant lead compound and has been
extensively investigated for its multiple bioactivities. Owing to its natural origin, non-toxic …
extensively investigated for its multiple bioactivities. Owing to its natural origin, non-toxic …
Design, synthesis, antifungal activity, and molecular docking studies of novel chiral isoxazoline-benzofuran-sulfonamide derivatives
Y Yan, A Bao, Y Wang, X **e, D Wang… - Journal of Agricultural …, 2024 - ACS Publications
Succinate dehydrogenase (SDH) is one of the most important molecular targets for the
development of novel fungicides. With the emerging problem of resistance in plant fungal …
development of novel fungicides. With the emerging problem of resistance in plant fungal …
Exploiting the biological efficacy of benzimidazole based Schiff base complexes with l-Histidine as a co-ligand: Combined molecular docking, DNA interaction …
Four new metal complexes were synthesized and screened for their cytotoxic activity after
sufficient assertion from the preliminary DNA binding studies. The metal complexes could …
sufficient assertion from the preliminary DNA binding studies. The metal complexes could …
Antioxidant activity and electrochemical elucidation of the enigmatic redox behavior of curcumin and its structurally modified analogues
Here, we report studies on the antioxidant activity and redox behavior of curcumin and its
structurally modified synthetic analogues. We have synthesized a number of analogues of …
structurally modified synthetic analogues. We have synthesized a number of analogues of …
Importance of fluorine in benzazole compounds
Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …
Structure activity relationship, cytotoxicity and evaluation of antioxidant activity of curcumin derivatives
PK Sahu, PK Sahu, PL Sahu, DD Agarwal - Bioorganic & medicinal …, 2016 - Elsevier
Abstract Series of curcumin derivatives/analogues were designed and efficient method for
synthesis thereof is described. All the synthesized compounds have been screened for their …
synthesis thereof is described. All the synthesized compounds have been screened for their …