Promising therapeutic strategies for colorectal cancer treatment based on nanomaterials

N Krasteva, M Georgieva - Pharmaceutics, 2022 - mdpi.com
Colorectal cancer (CRC) is a global health problem responsible for 10% of all cancer
incidences and 9.4% of all cancer deaths worldwide. The number of new cases increases …

Nano-enabled theranostics for cancer

P Sharmiladevi, K Girigoswami, V Haribabu… - Materials …, 2021 - pubs.rsc.org
This review focuses on the architecture and functions of theranostic nanoparticles. In the
beginning, this review highlights the importance of diagnostic imaging with a brief …

Targeted therapeutic effects of oral inulin-modified double-layered nanoparticles containing chemotherapeutics on orthotopic colon cancer

Y Hou, J **, H Duan, C Liu, L Chen, W Huang, Z Gao… - Biomaterials, 2022 - Elsevier
Colon cancer is emerging as one of the most prevalent cancers globally. Oral colonic drug
delivery systems have attracted considerable attention in the treatment of orthotopic colon …

Chitosan-based oral colon-specific delivery systems for polyphenols: recent advances and emerging trends

S Chen, H Zhu, Y Luo - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Oral colon-targeted delivery systems (OCDSs) have attracted great attention in the delivery
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …

Application of nanotechnology in the early diagnosis and comprehensive treatment of gastrointestinal cancer

S Deng, J Gu, Z Jiang, Y Cao, F Mao, Y Xue… - Journal of …, 2022 - Springer
Gastrointestinal cancer (GIC) is a common malignant tumour of the digestive system that
seriously threatens human health. Due to the unique organ structure of the gastrointestinal …

Current trends and future perspectives of nanomedicine for the management of colon cancer

S Wahab, MY Alshahrani, MF Ahmad… - European Journal of …, 2021 - Elsevier
Colon cancer (CC) kills countless people every year throughout the globe. It persists as one
of the highly lethal diseases to be treated because the overall survival rate for CC is meagre …

Antibacterial tellurium-containing polycarbonate drug carriers to eliminate intratumor bacteria for synergetic chemotherapy against colorectal cancer

J Hu, S Ran, Z Huang, Y Liu, H Hu, Y Zhou, X Ding… - Acta Biomaterialia, 2024 - Elsevier
Intratumor microbes have attracted great attention in cancer research due to its influence on
the tumorigenesis, progression and metastasis of cancer. However, the therapeutic …

Aptamer-mediated hollow MnO2 for targeting the delivery of sorafenib

Z Wang, C Wu, J Liu, S Hu, J Yu, Q Yin, H Tian… - Drug Delivery, 2023 - Taylor & Francis
Sorafenib (SRF) presents undesirable effects in clinical treatment, due to the lack of
targeting, poor water solubility, and obvious side effects. In this study, we constructed a …

Solid dispersions of gefitinib prepared by spray drying with improved mucoadhesive and drug dissolution properties

WW Mustafa, J Fletcher, M Khoder, RG Alany - AAPS PharmSciTech, 2022 - Springer
Gefitinib is a tyrosine kinase inhibitor that is intended for oral administration yet suffers poor
bioavailability along with undesirable side effects. To enhance its solubility and allow colon …

Mucoadhesive chitosan and thiolated chitosan nanoparticles containing alpha mangostin for possible Colon-targeted delivery

W Samprasit, P Opanasopit… - Pharmaceutical …, 2021 - Taylor & Francis
Abstract α-Mangostin-loaded mucoadhesive nanoparticles (NPs) were prepared for colon-
targeted drug delivery against colorectal cancer cells using pH-dependent composite …