Use of zebrafish in drug discovery toxicology
Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …
health and money. The drug discovery industry attempts to minimize those events with …
A review of practical statistical methods used in epidemiological studies to estimate the health effects of multi-pollutant mixture
L Yu, W Liu, X Wang, Z Ye, Q Tan, W Qiu, X Nie… - Environmental …, 2022 - Elsevier
Environmental risk factors have been implicated in adverse health effects. Previous
epidemiological studies on environmental risk factors mainly analyzed the impact of single …
epidemiological studies on environmental risk factors mainly analyzed the impact of single …
Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
[HTML][HTML] Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence
Objective We performed a systematic review of the epidemiology literature to identify the
neurodevelopmental effects associated with phthalate exposure. Data sources and study …
neurodevelopmental effects associated with phthalate exposure. Data sources and study …
Environmental exposure to low-level lead (Pb) co-occurring with other neurotoxicants in early life and neurodevelopment of children.
JG Dórea - Environmental Research, 2019 - Elsevier
Lead (Pb) is a worldwide environmental contaminant that even at low levels influences brain
development and affects neurobehavior later in life; nevertheless it is only a small fraction of …
development and affects neurobehavior later in life; nevertheless it is only a small fraction of …
Associations between the chemical exposome and pregnancy induced hypertension
Exposure to environmental chemicals has been linked to an increased risk of pregnancy-
induced hypertension (PIH). This prospective cohort study examined the associations …
induced hypertension (PIH). This prospective cohort study examined the associations …
[HTML][HTML] State-of-the-art methods for exposure-health studies: results from the exposome data challenge event
L Maitre, JB Guimbaud, C Warembourg… - Environment …, 2022 - Elsevier
The exposome recognizes that individuals are exposed simultaneously to a multitude of
different environmental factors and takes a holistic approach to the discovery of etiological …
different environmental factors and takes a holistic approach to the discovery of etiological …
[HTML][HTML] Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: evidence from mixture approaches
Background Air pollution is associated with accelerated biological ages determined by DNA
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …
[HTML][HTML] A case-control study on the association of mineral elements exposure and thyroid tumor and goiter
M Liu, J Song, Y Jiang, Y Liu, J Peng, H Liang… - Ecotoxicology and …, 2021 - Elsevier
Thyroid tumor and thyroid goiter are prevalent disease around the world. In this case-control
study, we investigated the association between exposure to a total of twelve mineral …
study, we investigated the association between exposure to a total of twelve mineral …
Impact of contaminants on microbiota: linking the gut–brain axis with neurotoxicity
Over the last years, research has focused on microbiota to establish a missing link between
neuronal health and intestine imbalance. Many studies have considered microbiota as …
neuronal health and intestine imbalance. Many studies have considered microbiota as …