Background: Suicidality is common in major depressive disorder (MDD), but there has been
no systematic review published about all aspects of suicidality. This meta-analysis and …

Abstract Purpose of Review Bipolar disorder has the highest rate of suicide of all psychiatric
conditions and is approximately 20–30 times that of the general population. The purpose of …

Abstract Background A once-weekly, 2.4-mg dose of subcutaneous semaglutide, a glucagon-
like peptide-1 receptor agonist, is used to treat obesity in adults, but assessment of the drug …

OBJECTIVES: Elevated rates of mental health concerns have been identified during the
coronavirus disease 2019 (COVID-19) pandemic. In this study, we sought to evaluate …

Background Posttraumatic stress disorder is a prevalent mental health condition with
substantial impact on daily functioning that lacks sufficient treatment options. Here we …

Objective: About one-third of patients with depression fail to achieve remission despite
treatment with multiple antidepressants. This study compared the efficacy and safety of …

Importance Controlled studies have shown short-term efficacy of esketamine for treatment-
resistant depression (TRD), but long-term effects remain to be established. Objective To …

Background About one-third of patients with depression fail to achieve remission despite
treatment with multiple antidepressants and are considered to have treatment-resistant …

Patients with treatment-resistant depression (TRD) have higher rates of relapse and
pronounced decreases in daily functioning and health-related quality of life compared to …

Background Suicide is a leading cause of death and a complex clinical outcome. Here, we
summarize the current state of research pertaining to suicidal thoughts and behaviors in …